Shedding quantitative fluorescence light on novel regulatory mechanisms in skeletal biomedicine and biodentistry.
Shedding quantitative fluorescence light on novel regulatory mechanisms in skeletal biomedicine and biodentistry.
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DOI：
10.1016/j.jdsr.2016.04.005
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发表时间：
2017-02
期刊：
影响因子：
--
通讯作者：
Iimura T
中科院分区：
文献类型：
--
作者：
Lee JW;Iimura T
数字化荧光图像包含诸如颜色（波长）、荧光强度和空间位置的数字信息。然而，对所获得数据的定量分析及其验证仍有待建立。我们的研究小组在组织切片上应用了定量荧光成像，并在骨骼生物医学和生物牙科学中发现了新的发现。本文简要介绍了定量荧光成像的背景，并通过介绍我们以前的研究讨论了实际应用。最后，对定量荧光成像的发展前景进行了展望。
Digitalized fluorescence images contain numerical information such as color (wavelength), fluorescence intensity and spatial position. However, quantitative analyses of acquired data and their validation remained to be established. Our research group has applied quantitative fluorescence imaging on tissue sections and uncovered novel findings in skeletal biomedicine and biodentistry. This review paper includes a brief background of quantitative fluorescence imaging and discusses practical applications by introducing our previous research. Finally, the future perspectives of quantitative fluorescence imaging are discussed.