The pK of five estrogens in aqueous solutions
The pK of five estrogens in aqueous solutions
复制标题
五种雌激素在水溶液中的 pK
DOI：
10.1016/0003-9861(67)90274-3
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发表时间：
1967
影响因子：
3.9
通讯作者：
M. J. Burgett
中科院分区：
文献类型：
--
作者：
R. Kirdani;M. J. Burgett
雌激素在酸性和碱性溶液中光谱的不同是由于苯氧离子的存在。因此，可以将缓冲溶液中的氢离子浓度与电离度联系起来。结果表明，雌二醇-17β的pK为10.078，雌二醇-17α的pK为10.098，雌酮为10.914，6-脱氢雌二醇为9.744，6-酮雌二醇为9.079。
The differences in spectra of estrogens in acidic and basic solutions are due to the presence of phenoxy ion. It is thus possible to relate hydrogen ion concentration in buffered solutions to degree of ionization. The pKof the estradiol-17β is thus found to be 10.078, that of estradiol-17α is 10.098, of estrone is 10.914, of 6-dehydroestradiol is 9.744, and of 6-ketoestradiol is 9.079.