Ensuring Safety and Functionality of Electroglottography Measurements during Dynamic Pulmonary MRI
Ensuring Safety and Functionality of Electroglottography Measurements during Dynamic Pulmonary MRI
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DOI：
10.1002/mrm.26037
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发表时间：
2016-11-01
影响因子：
3.3
通讯作者：
Bock, Michael
中科院分区：
文献类型：
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作者：
Ozen, Ali Caglar;Traser, Louisa;Bock, Michael
目的：将声道测量与肺部动态MRI相结合，为歌唱过程中肺部生理提供基本的见解。方法：为了分析动态肺MRI期间的声带振荡模式，对声门电图（EGG）系统进行了修改，以允许在MR图像采集期间同时测量EGG。引入低通滤波器抑制EGG信号中的残留射频耦合。在凝胶模体中测试射频加热以确保MR安全性，并在志愿者实验中评估EGG设备在A5至A3唱歌频率下的功能。在记录的EGG信号中，通过独立分量分析后处理去除剩余的射频干扰，计算出EGG的标准参数，如基频、接触商和抖动。在第二个志愿者实验中，将EGG记录与2D时间分辨trueFISP采集的肺直径测量结果进行比较。结果：射频加热测量导致凝胶模体温度升高不到1.2摄氏度。磁共振成像期间测量的EGG参数在理想值范围内。在肺测量中，肺直径和EGG记录都可以成功地进行，只有最小的干扰。结论：动态肺MRI可以记录EGG，在1.5T时可以安全地研究声门活动。(C) 2015国际医学磁共振学会
Purpose: To combine vocal tract measurements with dynamic MRI of the lungs to provide fundamental insights into the lung physiology during singing.Methods: To analyze vocal fold oscillatory patterns during dynamic lung MRI, an electroglottography (EGG) system was modified to allow for simultaneous EGG measurements during MR image acquisitions. A low-pass filter was introduced to suppress residual radiofrequency (RF) coupling into the EGG signal. RF heating was tested in a gel phantom to ensure MR safety, and functionality of the EGG device was assessed in a volunteer experiment at singing frequencies from A5 to A3. In the recorded EGG signals, remaining RF interferences were removed by independent component analysis post processing, and standard EGG parameters such as fundamental frequency, contact quotient and jitter were calculated. In a second volunteer experiment, EGG recordings were compared with lung diameter measurements from 2D time-resolved trueFISP acquisitions.Results: RF heating measurements resulted in less than 1.2 degrees C temperature increase in the gel phantom. EGG parameters measured during MR imaging are within the range of ideal values. In the lung measurement, both the lung diameter and the EGG recordings could be successfully performed with only minimal interference.Conclusion: EGG recording is possible during dynamic lung MRI, and glottal activity can be studied safely at 1.5T. (C) 2015 International Society for Magnetic Resonance in Medicine