New markers, D16FC1 and Tp12, differentiate between rat chromosomes 16 and 17.
New markers, D16FC1 and Tp12, differentiate between rat chromosomes 16 and 17.
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新标记 D16FC1 和 Tp12 可区分大鼠 16 号和 17 号染色体。
DOI：
10.1159/000133459
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发表时间：
1993
期刊：
影响因子：
--
通讯作者：
Testa,JR
中科院分区：
文献类型：
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作者：
Yeung,RS;Taguchi,T;Patriotis,C;Makris,A;Tsichlis,PN;Levan,KK;Levan,G;Tartof,K;Hino,O;Knudson,AG;Testa,JR
在细胞遗传学上区分大鼠16号和17号染色体的问题可以通过映射到这些染色体的独特探针来解决。通过体细胞杂交和非同位素原位杂交，将探针D16Fc1和Tp12分别定位于16p16→p15和17q12.1→q12.2。这些探针的位置可以作为参考点，便于将来将探针定位到大鼠的16号和17号染色体。
Problems in differentiating rat chromosomes 16 and 17 cytogenetically can be resolved with unique probes mapped to these chromosomes. Using somatic cell hybridization and nonisotopic in situ hybridization, probes D16FC1 and Tp12 were localized to 16p16→p15 and 17q12.1→q12.2, respectively. The locations of these probes can serve as reference points to facilitate mapping of future probes to rat chromosomes 16 and 17.