Implementation of Quantitative Perfusion Imaging Using Pulsed Arterial Spin Labeling at Ultra-High Field
Implementation of Quantitative Perfusion Imaging Using Pulsed Arterial Spin Labeling at Ultra-High Field
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DOI：
10.1002/mrm.21796
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发表时间：
2009-04-01
影响因子：
3.3
通讯作者：
Francis, S. T.
中科院分区：
文献类型：
--
作者：
Gardener, A. G.;Gowland, P. A.;Francis, S. T.
本研究比较了星星和FAIR脉冲动脉自旋标记（PASL）方案在超高场（7 T）和高场（3 T）下形成定量灌注图的实施。进行体模实验以比较在7 T和3 T下的标记脉冲的反转效率和轮廓，并优化面内饱和技术。灌注加权（PW）信号测量在一系列的标记后延迟时间和定量灌注图上逐体素计算的基础上。PW信号随场强增加而增加，并且信噪比增加，这导致图像信噪比和7 T灌注图拟合质量改善。Magn Reson Med 61：874-882，2009. (C)2009 Wiley-Liss，Inc.
This study compares the implementation of the STAR and FAIR pulsed arterial spin labeling (PASL) schemes to form quantitative perfusion maps at ultra-high field, 7 Tesla (T), and high field, 3T. Phantom experiments were performed to compare the inversion efficiency and profile of the labeling pulses at 7T and 3T and to optimize in-plane saturation techniques. The perfusion weighted (PW) signal was measured at a range of postlabeling delay times and quantitative perfusion maps were calculated on a voxel-by-voxel basis. An increase in PW signal was found with field strength, and together with the increased signal-to-noise ratio, this led to improved image signal-to-noise and quality of fit of perfusion maps at 7T. Magn Reson Med 61:874-882, 2009. (C) 2009 Wiley-Liss, Inc.