Alginate/cashew gum nanoparticles for essential oil encapsulation
Alginate/cashew gum nanoparticles for essential oil encapsulation
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DOI：
10.1016/j.colsurfb.2013.08.038
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发表时间：
2014-01-01
影响因子：
5.8
通讯作者：
de Paula, Regina C. M.
中科院分区：
文献类型：
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作者：
de Oliveira, Erick F.;Paula, Haroldo C. B.;de Paula, Regina C. M.
通过喷雾干燥法制备了海藻酸盐/腰果胶纳米粒子，旨在开发一种用于精油胶囊的生物聚合物共混物。通过红外光谱(FT-IR)、热分析(TGA/DSC)和X射线衍射仪(X-射线衍射仪)对纳米粒的流体力学体积、表面电荷、山麦冬挥发油含量和释放度进行了表征。溶液中的纳米粒子的平均尺寸在223-399 nm之间，Zeta电位值在-30-36 mV之间。包埋油含量从1.9%到4.4%不等，包封率高达55%。体外释放曲线显示，45%-95%的油在30-50h内被释放。动力学研究表明，其释药规律遵循Korsmeyer-Peppas机理。(C)2013爱思唯尔B.V.保留所有权利。
Alginate/cashew gum nanoparticles were prepared via spray-drying, aiming at the development of a biopolymer blend for encapsulation of an essential oil. Nanoparticles were characterized regarding to their hydrodynamic volume, surface charge, Lippia sidoides essential oil content and release profile, in addition to being analyzed by infrared spectroscopy (FT-IR), thermal analysis (TGA/DSC) and X-ray diffractometry. Nanoparticles in solution were found to have averaged sizes in the range 223-399 nm, and zeta potential values ranging from -30 to -36 mV. Encapsulated oil levels varied from 1.9 to 4.4% with an encapsulation efficiency of up to 55%. The in vitro release profile showed that between 45 and 95% of oil was released within 30-50h. Kinetic studies revealed that release pattern follow a Korsmeyer-Peppas mechanism. (C) 2013 Elsevier B.V. All rights reserved.