Distinct phenotypic features of neonatal murine macrophages
Distinct phenotypic features of neonatal murine macrophages
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DOI：
10.1002/eji.201444468
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发表时间：
2015-01-01
影响因子：
5.4
通讯作者：
Kuebler, Joachim F.
中科院分区：
文献类型：
--
作者：
Winterberg, Thomas;Vieten, Gertrud;Kuebler, Joachim F.
新生儿依靠他们的先天免疫系统。驻留组织巨噬细胞被认为是先天性免疫应答的启动子和调节子，因此似乎对新生儿特别重要。我们假设新生儿组织巨噬细胞的表型和功能与成年巨噬细胞不同。新生儿腹膜巨噬细胞（
Neonates rely on their innate immune system. Resident tissue macrophages are considered to be initiators and regulators of the innate immune response and thus, appear to be especially important to neonates. We hypothesized that the phenotype and function of neonatal tissue macrophages differ from their adult counterparts. Peritoneal macrophages from neonatal (