Use of out-of-hospital cardiac arrest registries to assess COVID-19 home mortality.
Use of out-of-hospital cardiac arrest registries to assess COVID-19 home mortality.
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DOI：
10.1186/s12874-020-01189-3
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发表时间：
2020-12-14
影响因子：
4
通讯作者：
Chazard E
中科院分区：
文献类型：
--
作者：
Hubert H;Baert V;Beuscart JB;Chazard E
在大多数国家，2019年冠状病毒病（COVID-19）的官方统计数据考虑了住院死亡人数，但没有考虑在家中发生的死亡人数。该研究的目的是通过分析法国国家院外心脏骤停（OHCA）登记处（RéAC），引入一种评估COVID-19家庭死亡的方法。我们根据2020年3月1日至4月15日期间20个移动的医疗团队（MMT）在RéAC中记录的数据进行了一项回顾性多中心队列研究。参与的MMT覆盖了法国人口的10.1%。OHCA患者被分类为可能或确诊的COVID-19病例或非COVID-19病例。为了实现我们的主要目标，我们计算了在家中发生的COVID-19 OHCA病例的发病率和入院时的生存率。排除了发生在养老院或公共场所的心脏骤停。因此，我们估计了法国国家统计数据中未计入的COVID-19相关居家死亡人数。我们纳入了670例OHCA患者。OHCA的外推年发病率为每100，000名居民91. 9人，而COVID-19 OHCA在家中的发病率为17. 6人。在后一组中，OHCA后被送往医院的生存率为10.9%。我们估计，在2020年4月15日的法国国家统计数据中，有1322人死亡。COVID-19医院外死亡与医院内死亡的比例为12. 4%，因此国家统计数据低估了死亡率。
In most countries, the official statistics for the coronavirus disease 2019 (COVID-19) take account of in-hospital deaths but not those that occur at home. The study’s objective was to introduce a methodology to assess COVID-19 home deaths by analysing the French national out-of-hospital cardiac arrest (OHCA) registry (RéAC). We performed a retrospective multicentre cohort study based on data recorded in the RéAC by 20 mobile medical teams (MMTs) between March 1st and April 15th, 2020. The participating MMTs covered 10.1% of the French population. OHCA patients were classified as probable or confirmed COVID-19 cases or as non-COVID-19 cases. To achieve our primary objective, we computed the incidence and survival at hospital admission of cases of COVID-19 OHCA occurring at home. Cardiac arrests that occurred in retirement homes or public places were excluded. Hence, we estimated the number of at-home COVID-19-related deaths that were not accounted for in the French national statistics. We included 670 patients with OHCA. The extrapolated annual incidence of OHCA per 100,000 inhabitants was 91.9 overall and 17.6 for COVID-19 OHCA occurring at home. In the latter group, the survival rate after being taken to the hospital after an OHCA was 10.9%. We estimated that 1322 deaths were not accounted in the French national statistics on April 15, 2020. The ratio of COVID-19 out-of-hospital deaths to in-hospital deaths was 12.4%, and so the national statistics underestimated the death rate.
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影响因子：
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作者：
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DOI：
10.1073/pnas.2004064117
发表时间：
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影响因子：
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