A polychromatic 'greenbeard' locus determines patterns of cooperation in a social amoeba.
A polychromatic 'greenbeard' locus determines patterns of cooperation in a social amoeba.
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DOI：
10.1038/ncomms14171
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发表时间：
2017-01-25
影响因子：
16.6
通讯作者：
Thompson CR
中科院分区：
文献类型：
--
作者：
Gruenheit N;Parkinson K;Stewart B;Howie JA;Wolf JB;Thompson CR
作弊者通过收获利益而不支付其公平份额的相关成本来破坏合作。如果合作者展示标签（“绿胡子”）并识别并优先指导与其他标签携带者的合作，则可以减少作弊者的影响。尽管这种绿胡子广受欢迎，但其可行性受到质疑，因为自然界中所见的合作伙伴特定合作行为的复杂模式要求绿胡子具有不同的颜色。在这里，我们表明，一个轨迹（'TGR'）的社会阿米巴代表多色绿胡子。天然Tgr基因座序列多态性的模式预测合作伙伴特定的合作模式的潜在变化的合作伙伴特定的蛋白质-蛋白质结合强度和识别特异性。最后，Tgr基因座多态性增加健身，因为它们有助于避免与不相容的合作伙伴合作的潜在成本。这些结果表明，多色绿胡子可以提供一个关键的机制，进化的合作维护。如果合作者能够可靠地相互识别，合作就可以稳定下来，不受剥削。在这里，Gruenfeld和同事们表明，社会性阿米巴Dictyosteelium discoideum的Tgr基因座的不同等位基因是不同菌株识别和与社会相容个体合作的能力的基础。
Cheaters disrupt cooperation by reaping the benefits without paying their fair share of associated costs. Cheater impact can be diminished if cooperators display a tag (‘greenbeard') and recognise and preferentially direct cooperation towards other tag carriers. Despite its popular appeal, the feasibility of such greenbeards has been questioned because the complex patterns of partner-specific cooperative behaviours seen in nature require greenbeards to come in different colours. Here we show that a locus (‘Tgr') of a social amoeba represents a polychromatic greenbeard. Patterns of natural Tgr locus sequence polymorphisms predict partner-specific patterns of cooperation by underlying variation in partner-specific protein–protein binding strength and recognition specificity. Finally, Tgr locus polymorphisms increase fitness because they help avoid potential costs of cooperating with incompatible partners. These results suggest that a polychromatic greenbeard can provide a key mechanism for the evolutionary maintenance of cooperation. Cooperation can be stabilized against exploitation if cooperators can reliably recognize each other. Here, Gruenheit and colleagues show that different alleles of the Tgr locus of the social amoeba Dictyostelium discoideum underlie the ability of different strains to recognize and cooperate with socially compatible individuals.