Patterns of Genomic Diversity in a Fig-Associated Close Relative of Caenorhabditis elegans
Patterns of Genomic Diversity in a Fig-Associated Close Relative of Caenorhabditis elegans
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DOI：
10.1093/gbe/evae020
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发表时间：
2024-02-01
影响因子：
3.3
通讯作者：
Phillips，Patrick C.
中科院分区：
文献类型：
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作者：
Woodruff，Gavin C.;Willis，John H.;Phillips，Patrick C.
繁殖方式的进化将对种群的遗传组成产生深远的影响。与此同时，生态相互作用可以使物种之间产生紧密的关联，这反过来又可以使它们的空间分布产生高度的重叠。秀丽隐杆线虫（Caelophabditis elegansis）是一种两性线虫，使发育遗传学的研究取得了广泛的进展。elegans是一种生殖分布线虫，在无花果中生长旺盛，专性地散布在无花果小蜂上。在这里，我们描述了模式的基因组多样性在C。inopinata。我们对从冲绳三个岛屿种群中分离的个体蠕虫进行了RAD-seq。inopinatais约五倍以上的多样性比C.优雅的此外，还发现C. inopinata在功能基因组区域之间（如基因序列和基因间序列之间）的多样性差异比C.优美的反之，C.在高重组染色体臂和低重组染色体中心的多样性上，香兰的差异比C.岛屿种群对间的FST较低，岛屿间的种群结构不明显，表明岛屿间的胡蜂迁徙频繁。这些模式的人口分化出现与以前报道的无花果小蜂载体。这些结果证实了许多理论群体遗传预测有关的生殖方式的演变和approxistC。inopinata种群动态可能是由黄蜂扩散驱动的。这项工作为未来的进化基因组研究奠定了基础，旨在了解性别的进化以及生态相互作用的进化。
The evolution of reproductive mode is expected to have profound impacts on the genetic composition of populations. At the same time, ecological interactions can generate close associations among species, which can in turn generate a high degree of overlap in their spatial distributions.Caenorhabditis elegansis a hermaphroditic nematode that has enabled extensive advances in developmental genetics.Caenorhabditis inopinata, the sister species ofC. elegans, is a gonochoristic nematode that thrives in figs and obligately disperses on fig wasps. Here, we describe patterns of genomic diversity inC. inopinata. We performed RAD-seq on individual worms isolated from the field across three Okinawan island populations.C. inopinatais about five times more diverse thanC. elegans. Additionally,C. inopinataharbors greater differences in diversity among functional genomic regions (such as between genic and intergenic sequences) thanC. elegans. Conversely,C. elegansharbors greater differences in diversity between high-recombining chromosome arms and low-recombining chromosome centers thanC. inopinata.FSTis low among island population pairs, and clear population structure could not be easily detected among islands, suggesting frequent migration of wasps between islands. These patterns of population differentiation appear comparable with those previously reported in its fig wasp vector. These results confirm many theoretical population genetic predictions regarding the evolution of reproductive mode and suggestC. inopinatapopulation dynamics may be driven by wasp dispersal. This work sets the stage for future evolutionary genomic studies aimed at understanding the evolution of sex as well as the evolution of ecological interactions.