Structure-activity relationship of the tocopherol-regeneration reaction by catechins

Structure-activity relationship of the tocopherol-regeneration reaction by catechins
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DOI:
10.1016/j.freeradbiomed.2005.01.011
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发表时间:
2005-05-01
影响因子:
7.4
通讯作者:
Nagaoka, SI
Nagaoka, SI
中科院分区:
医学1区
文献类型:
--
作者:
Mukai, K;Mitani, S;Nagaoka, SI

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用停流分光光度计测定了5,7-二异丙基生育酚氧自由基(Toc)与儿茶素类(表儿茶素(EC)、表儿茶素没食子酸酯(ECG)、表没食子儿茶素(EGC)、表没食子儿茶素没食子酸酯(EGCG))及其相关化合物(没食子酸甲酯(MG)、4-甲基儿茶酚(MC)和5-甲氧基间苯二酚(MR))的反应速率(k(r))。k(r)值按MR的顺序增加
The reaction rates (k(r)) of 5,7-diisopropyl-tocopheroxyl radical (Toc(center dot)) with catechins (epicatechin (EC), epicatechin gallate (ECG), epigallocatechin (EGC), epigoallocatechin gallate (EGCG)) and related compounds (methyl gallate (MG), 4-methyleatechol (MC), and 5-Foethoxyresorcinol (MR)) have been measured by stopped-flow spectrophotorneter. The k(r), values increased in the order of MR