Postoperative Quality of Life: Development and Validation of the "Dysfunction after Upper Gastrointestinal Surgery" Scoring System
Postoperative Quality of Life: Development and Validation of the "Dysfunction after Upper Gastrointestinal Surgery" Scoring System
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DOI：
10.1016/j.jamcollsurg.2011.07.007
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发表时间：
2011-10-01
影响因子：
5.2
通讯作者：
Lefor, Alan T.
中科院分区：
文献类型：
--
作者：
Nakamura, Misuzu;Hosoya, Yoshinori;Lefor, Alan T.
背景技术背景：虽然术后生活质量是一个重要的结果的措施，很少有工具存在，以评估患者的具体后上消化道手术。先前开发的上消化道手术后功能障碍（DAUGS）32评分系统已进一步完善，仅包括20个项目。研究设计：本研究是作为一项调查进行的，在3个独立的institutions.RESULTS：胃切除术后（n = 662）和食管切除术后（n = 221）的DAUGS 20评分为27.8，36.1，显示出显着差异（P < 0.05）后，上消化道切除术后的患者。远端胃切除术后282例患者的评分为25.4分，全胃切除术后149例患者的评分为32.0分，差异有显著性（P < 0.05）。DAUGS 20系统各项目的α系数为0.904，各分量表的Cronbach’s α系数为0.612 ~ 0.856，表明该评估工具具有较高的信度。此外，从20个项目中提取7个因素，使用确定性因素分析，以验证validity.CONCLUSIONS：患者的生活质量应作为手术切除后的结果进行评估癌症，就像总生存率进行分析。DAUGS 20评分可靠，对术后患者的评价具有效度，是评估癌症上消化道手术后患者生活质量的有价值的工具。（美国科尔外科杂志2011;213：508-514。(C)2011年美国外科医生学会）
BACKGROUND: Although postoperative quality of life is an important outcomes measure, few tools exist to evaluate patients specifically after upper gastrointestinal surgery. The previously developed Dysfunction After Upper Gastrointestinal Surgery (DAUGS) 32 scoring system has been further refined to include just 20 items. This study was undertaken to validate the refined evaluation tool.STUDY DESIGN: The study was performed as a survey, administered to patients after upper gastrointestinal resection at 3 separate institutions.RESULTS: The DAUGS20 score after gastrectomy (n = 662) was 27.8 and that after esophagectomy (n = 221) was 36.1, showing a significant difference (p < 0.05). The score after distal gastrectomy (n = 282) was 25.4 and that after total gastrectomy (n = 149) was 32.0, showing a significant (p < 0.05) difference. The alpha coefficient of all items on the DAUGS20 system was 0.904 and Cronbach's alpha coefficients of the subscales were 0.612 to 0.856, demonstrating high reliability of this evaluation tool. In addition, 7 factors were extracted from the 20 items using definitive factor analysis, to verify validity.CONCLUSIONS: Patient quality of life should be evaluated as an outcomes measure after surgical resection for cancer, just as overall survival is analyzed. The DAUGS20 score is reliable, has validity in the evaluation of postoperative patients, and is a valuable tool to assess patient quality of life after upper gastrointestinal surgery for cancer. (J Am Coll Surg 2011;213:508-514. (C) 2011 by the American College of Surgeons)