Lack of a Tricuspid Regurgitation Doppler Signal and Pulmonary Hypertension by Invasive Measurement
Lack of a Tricuspid Regurgitation Doppler Signal and Pulmonary Hypertension by Invasive Measurement
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DOI：
10.1161/jaha.118.009362
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发表时间：
2018-07-03
影响因子：
5.4
通讯作者：
Brittain, Evan L.
中科院分区：
文献类型：
--
作者：
O'Leary, Jared M.;Assad, Tufik R.;Brittain, Evan L.
背景-经胸超声心动图（TTE）用于估计肺动脉收缩压，但并不总是存在计算肺动脉收缩压所需的足够的三尖瓣返流速度（TRV）。目前尚不清楚是否存在可测量的TRV意味着正常的肺动脉pressure.Methods和Results-We提取血流动力学，TTE，和临床数据从范德比尔特的去识别的电子病历在1998年和2014年之间的所有患者的右心导管插入术。肺动脉高压（PH）定义为平均肺动脉压>= 25 mm Hg。我们研究了没有报告TRV的患者中PH的患病率和临床相关性。我们确定了1262例在右心导管插入术后2天内发生TTE的患者。总的来说，803/1262例（64%）报告了TRV，而459例（36%）未报告TRV。在未报告TRV的患者中，47%的患者存在侵袭性PH，而在报告TRV的患者中，68%的患者存在侵袭性PH（P
Background-Transthoracic echocardiography (TTE) is used to estimate pulmonary artery systolic pressure, but an adequate tricuspid regurgitation velocity (TRV) needed to calculate pulmonary artery systolic pressure is not always present. It is unknown whether the absence of a measurable TRV signifies normal pulmonary artery pressure.Methods and Results-We extracted hemodynamic, TTE, and clinical data from Vanderbilt's deidentified electronic medical record in all patients referred for right heart catheterization between 1998 and 2014. Pulmonary hypertension (PH) was defined as mean pulmonary artery pressure >= 25 mm Hg. We examined the prevalence and clinical correlates of PH in patients without a reported TRV. We identified 1262 patients with a TTE within 2 days of right heart catheterization. In total, 803/1262 (64%) had a reported TRV, whereas 459 (36%) had no reported TRV. Invasively confirmed PH was present in 47% of patients without a reported TRV versus 68% in those with a reported TRV (P