Wake up of transposable elements following Drosophila simulans worldwide colonization.

Wake up of transposable elements following Drosophila simulans worldwide colonization.
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模拟果蝇在全球定植后转座因子的觉醒。

DOI:
10.1093/oxfordjournals.molbev.a026215
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发表时间:
1999
影响因子:
10.7
通讯作者:
C. Biémont
C. Biémont
中科院分区:
生物学1区
文献类型:
--
作者:
C. Vieira;D. Lepetit;Sandy Dumont;C. Biémont

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转座因子(Transposable elements,TE)约占果蝇基因组的10%-15%,但其姊妹种拟果蝇(Drosophila simulans)仅携带三分之一的此类重复序列。然而,我们没有一个全面的看法,在这两个物种的自然种群的基因组中的各种类型的TE(长末端重复序列[LTR]反转录转座子,非LTR反转录转座子和转座子)的拷贝数。我们分析了34个元素,从这些物种的各种自然种群的个人。我们证明了D.黑腹果蝇平均每个基因组的染色体插入位点数高于果蝇。除了五个外,所有TE都是模拟的。LTR反转录转座子gypsy、扎姆和1731以及转座子巴里-1在两个物种中呈现相似的低拷贝数。转座子流浪汉有大量的插入位点,在D. simulans。D.某些元件的插入位点数在居群间变异较大。simulans认为,这些元素可以从当地种群开始侵入整个物种的基因组。我们建议在D. simulans基因组被唤醒和扩增,就像很久以前在D.黑腹菌
Transposable elements (TEs) make up around 10%-15% of the Drosophila melanogaster genome, but its sibling species Drosophila simulans carries only one third as many such repeat sequences. We do not, however, have an overall view of copy numbers of the various classes of TEs (long terminal repeat [LTR] retrotransposons, non-LTR retrotransposons, and transposons) in genomes of natural populations of both species. We analyzed 34 elements in individuals from various natural populations of these species. We show that D. melanogaster has higher average chromosomal insertion site numbers per genome than D. simulans for all TEs except five. The LTR retrotransposons gypsy, ZAM, and 1731 and the transposon bari-1 present similar low copy numbers in both species. The transposon hobo has a large number of insertion sites, with significantly more sites in D. simulans. High variation between populations in number of insertion sites of some elements of D. simulans suggests that these elements can invade the genome of the entire species starting from a local population. We propose that TEs in the D. simulans genome are being awakened and amplified as they had been a long time ago in D. melanogaster.
DOI: 10.1016/0168-9525(92)90281-8
发表时间: 1992
期刊: Trends in genetics : TIG
影响因子: --
作者:
Aquadro,CF
通讯作者: Aquadro,CF
DOI: 10.1093/genetics/150.2.777
发表时间: 1998
期刊: Genetics
影响因子: 3.3
作者:
Irvin,SD;Wetterstrand,KA;Hutter,CM;Aquadro,CF
通讯作者: Aquadro,CF
DOI: 10.1093/oxfordjournals.molbev.a040491
发表时间: 1988
影响因子: 10.7
作者:
Anxolabéhère,D;Kidwell,MG;Periquet,G
通讯作者: Periquet,G
DOI: 10.1093/genetics/119.4.875
发表时间: 1988
期刊: Genetics
影响因子: 3.3
作者:
Aquadro,CF;Lado,KM;Noon,WA
通讯作者: Noon,WA