β-glucans in promoting health:: Prevention against mutation and cancer

β-glucans in promoting health:: Prevention against mutation and cancer
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DOI:
10.1016/j.mrrev.2007.07.002
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发表时间:
2008-03-01
影响因子:
5.3
通讯作者:
Ribeiro, Lucia R.
Ribeiro, Lucia R.
中科院分区:
医学2区
文献类型:
--
作者:
Mantovani, Mario S.;Bellini, Marilanda F.;Ribeiro, Lucia R.

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多糖-葡聚糖是细胞壁的主要成分。一些微生物,如酵母和蘑菇,以及燕麦和大麦等谷物,具有经济价值,因为它们含有大量的-葡聚糖。这些物质刺激免疫系统,调节体液和细胞免疫,从而对抵抗感染(细菌、病毒、真菌和寄生虫)有有益的作用。-葡聚糖还具有降低胆固醇和抗凝血的特性。近年来,它们已被证明具有抗细胞毒性、抗诱变性和抗肿瘤性,使其成为有希望的健康药理促进剂。(C) 2008 Elsevier B.V.版权所有
The polysaccharides beta-glucans occur as a principal component of the cellular walls. Some microorganisms, such as yeast and mushrooms, and also cereals such as oats and barley, are of economic interest because they contain large amounts of beta-glucans. These substances stimulate the immune system, modulating humoral and cellular immunity, and thereby have beneficial effect in fighting infections (bacterial, viral, fungal and parasitic). beta-Glucans also exhibit hypocholesterolemic and anticoagulant properties. Recently, they have been demonstrated to be anti-cytotoxic, antimutagenic and anti-tumorogenic, making them promising candidate as pharmacological promoters of health. (C) 2008 Elsevier B.V. All rights reserved.