Mucocutaneous lesions of Behcet's disease.

Mucocutaneous lesions of Behcet's disease.
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Behcet病的粘膜皮肤病变。

DOI:
10.3349/ymj.2007.48.4.573
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发表时间:
2007-08-31
影响因子:
2.4
通讯作者:
Ehrlich GE
Ehrlich GE
中科院分区:
医学4区
文献类型:
--
作者:
Alpsoy E;Zouboulis CC;Ehrlich GE

文献摘要

被引文献

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白塞氏病在“丝绸之路”人群中尤其流行,但它具有全球分布。该疾病的诊断基于临床标准,因为目前还没有特征性测试,并且在表现和诊断中占显着地位的粘膜皮肤病变可以被认为是诊断标志。在国际公认的标准中,疼痛的口腔和生殖器溃疡、皮肤血管炎病变以及皮肤对针刺或注射的反应(过敏反应)被认为是白塞氏病的标志,并且通常先于其他表现。他们的认识可能允许更早的诊断和治疗,并产生有益的结果。本文描述了构成该综合征的各种病变,并重点关注那些可能被认为具有特征性的病变。
Behçet's disease is particularly prevalent in "Silk Route" populations, but it has a global distribution. The diagnosis of the disease is based on clinical criteria as there is as yet no pathognomonic test, and mucocutaneous lesions, which figure prominently in the presentation and diagnosis, may be considered the diagnostic hallmarks. Among the internationally accepted criteria, painful oral and genital ulcers, cutaneous vasculitic lesions and reactivity of the skin to needle prick or injection (the pathergy reaction) are considered hallmarks of Behçet's disease, and often precede other manifestations. Their recognition may permit earlier diagnosis and treatment, with salutary results. This paper describes the various lesions that constitute the syndrome and focuses on those that may be considered characteristic.