THE ASSOCIATION OF GIRTH MEASUREMENTS WITH DISEASE IN 32,856 WOMEN
THE ASSOCIATION OF GIRTH MEASUREMENTS WITH DISEASE IN 32,856 WOMEN
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DOI：
10.1093/oxfordjournals.aje.a113727
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发表时间：
1984-01-01
影响因子：
5
通讯作者：
RIMM, AA
中科院分区：
文献类型：
--
作者：
HARTZ, AJ;RUPLEY, DC;RIMM, AA
大多数评估肥胖与疾病之间关系的流行病学研究仅考虑总脂肪组织而忽略其分布。本研究使用了 1969 年 TOPS（减肥组织）全国女性调查的数据。本研究的目的是通过对 21,065 名 40-59 岁女性和 11,791 名 20-39 岁女性的周长、身高和体重测量，评估脂肪组织的分布作为疾病的危险因素。身体脂肪分布指数，即腰围与臀围的比率，与 40-59 岁女性的糖尿病、高血压和胆囊疾病以及 20-39 岁女性的月经异常显着相关。即使在全身脂肪相当的女性中，腰部脂肪相对较多（与臀部相比）也与较高的疾病患病率相关。仅基于体重和身高的指数可能无法充分表征与肥胖相关的风险。
Most epidemiologic studies which evaluate the association between obesity and disease consider only total adipose tissue and ignore its distribution. The present study used data from a national survey of women in TOPS (a weight reduction organization) in 1969. The purpose of this study was to evaluate the distribution of adipose tissue as a risk factor for disease using girth, height, and weight measurements in 21,065 women 40-59 yr of age and 11,791 women 20-39 yr of age. An index of body fat distribution, the ratio of waist girth to hip girth, was significantly associated with diabetes, hypertension, and gallbladder disease in women aged 40-59 and with menstrual abnormalities in women aged 20-39. Relatively more fat around the waist (as compared to hips) was associated with higher disease prevalence even among women with comparable total body fat. Indices based only on weight and height may not adequately characterize the risks associated with obesity.