Review: Risk of Cerebrovascular Adverse Events and Death in Elderly Patients With Dementia When Treated With Antipsychotic Medications: A Literature Review of Evidence
Review: Risk of Cerebrovascular Adverse Events and Death in Elderly Patients With Dementia When Treated With Antipsychotic Medications: A Literature Review of Evidence
复制标题
综述：老年痴呆症患者接受抗精神病药物治疗时发生脑血管不良事件和死亡的风险：证据文献综述
DOI：
--
复制
发表时间：
2011
影响因子：
3.4
通讯作者：
R. Tampi
中科院分区：
文献类型：
--
作者：
Vikrant Mittal;L. Kurup;D. Williamson;Sunanda Muralee;R. Tampi
Behavioral and Psychological Symptoms of Dementia (BPSD) are increasingly recognized as a major risk factor for caregiver burden, institutionalization, greater impairment in activities of daily living (ADLs), more rapid cognitive decline, and a poorer quality of life. BPSD contribute significantly to the direct and indirect costs of caring for patients with dementia even after adjusting for the severity of cognitive impairment and other co-morbidities. Research on these symptoms has indicated a complex interplay between the biological, psychological and social factors involved in the disease process. Although some psychotropic medications have shown modest efficacy in the treatment of these behaviors, their use has generated controversy due to increasing recognition of the side effects of these medications especially the antipsychotic medications. In this review, we examine the risk of cerebrovascular adverse events (CVAEs) and death with antipsychotic medications when used to treat elderly patients with dementia.
轻度至中度阿尔茨海默病的精神病理学特征的过程。
影响因子：
--
作者：
Devanand,DP;Jacobs,DM;Tang,MX;DelCastillo-Castaneda,C;Sano,M;Marder,K;Bell,K;Bylsma,FW;Brandt,J;Albert,M;Stern,Y
通讯作者：
Stern,Y
DOI：
10.4088/jcp.08m04828
发表时间：
2009-06
期刊：
The Journal of clinical psychiatry
影响因子：
--
作者：
Siddique H;Hynan LS;Weiner MF
通讯作者：
Weiner MF
阿尔茨海默病患者与第二代抗精神病药物使用相关的代谢变化：CATIE-AD 研究。
DOI：
10.1176/appi.ajp.2008.08081218
发表时间：
2009
期刊：
The American journal of psychiatry
影响因子：
--
作者：
Zheng,Ling;Mack,WendyJ;Dagerman,KarenS;Hsiao,JohnK;Lebowitz,BarryD;Lyketsos,ConstantineG;Stroup,TScott;Sultzer,DavidL;Tariot,PierreN;Vigen,Cheryl;Schneider,LonS
通讯作者：
Schneider,LonS