Pain and Psychology-A Reciprocal Relationship.
Pain and Psychology-A Reciprocal Relationship.
复制标题
疼痛与心理学——相互的关系。
作者：
N. Vadivelu;Alice M. Kai;Gopal Kodumudi;Karine Babayan;M. Fontes;M. Burg
背景
抑郁症通常影响5%的普通人群，但在慢性疼痛患者中，30%-45%的人患有抑郁症。研究表明，抑郁和疼痛之间的关系是双向的：抑郁是慢性疼痛发展的积极预测因素，慢性疼痛会增加抑郁的风险。
方法
这篇文献综述的重点是心理学和疼痛之间的关系，涵盖了研究抑郁症，疼痛敏感性，阿片类药物滥用和疼痛感知的性别差异之间的关联。我们进行了PubMed搜索，将疼痛与抑郁症，阿片类药物使用和性别差异配对。
结果
抑郁症和疼痛之间的关系是复杂的，正如许多研究所表明的那样，抑郁症是疼痛严重程度，身体功能和阿片类药物使用之间关系的调节剂。神经影像学也表明慢性疼痛和抑郁症的途径解剖重叠。积极的心理因素，即希望，疼痛接受和乐观，影响持续疼痛的调整。
结论
疼痛和心理之间的复杂关系可以通过临床表现的重叠以及与疼痛的情感和感觉特征相关的大脑解剖区域与受抑郁影响的区域之间的重叠来证明。研究开始提高我们对这两个系统的理解，但需要更多的研究来阐明这种关系。
BACKGROUND
Depression typically affects 5% of the general population, but among patients with chronic pain, 30%-45% experience depression. Studies have shown that the relationship between depression and pain is bidirectional: depression is a positive predictor of the development of chronic pain, and chronic pain increases the risk of developing depression.
METHODS
This literature review focuses on the relationship between psychology and pain, covering studies that have investigated the association between depression, pain sensitivity, opioid abuse, and gender differences in pain perception. We conducted a PubMed search pairing the word pain with depression, opioid use, and gender differences.
RESULTS
The relationship between depression and pain is complex, as suggested by numerous studies that propose depression to be a moderator of the relationship between pain severity, physical functioning, and opioid use. Neuroimaging also suggests an anatomic overlap in the pathway of chronic pain and depression. Positive psychological factors, namely hope, pain acceptance, and optimism, affect the adjustment to persistent pain.
CONCLUSION
The intricate relationship between pain and psychology is evidenced by the clinical overlap in their presentations and the overlap between the anatomic regions in the brain associated with the emotional and sensory features of pain and the areas affected by depression. Studies are beginning to improve our understanding of these two systems, but more studies are needed to elucidate the relationship.
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DOI：
10.1016/j.jpain.2008.10.008
发表时间：
2009-02
期刊：
The journal of pain
影响因子：
--
作者：
Chou R;Fanciullo GJ;Fine PG;Adler JA;Ballantyne JC;Davies P;Donovan MI;Fishbain DA;Foley KM;Fudin J;Gilson AM;Kelter A;Mauskop A;O'Connor PG;Passik SD;Pasternak GW;Portenoy RK;Rich BA;Roberts RG;Todd KH;Miaskowski C;American Pain Society-American Academy of Pain Medicine Opioids Guidelines Panel
通讯作者：
American Pain Society-American Academy of Pain Medicine Opioids Guidelines Panel
影响因子：
4
作者：
Miller, Lisa Renee;Cano, Annmarie
通讯作者：
Cano, Annmarie
影响因子：
4
作者：
Hirsh, Adam T.;George, Steven Z.;Robinson, Michael E.
通讯作者：
Robinson, Michael E.
DOI：
10.1016/j.jpain.2015.12.012
发表时间：
2016-04
期刊：
The journal of pain
影响因子：
--
作者：
Scherrer JF;Salas J;Copeland LA;Stock EM;Schneider FD;Sullivan M;Bucholz KK;Burroughs T;Lustman PJ
通讯作者：
Lustman PJ
影响因子：
5.3
作者：
Karp, JF;Scott, J;Frank, E
通讯作者：
Frank, E