Vitamin A status and therapy in childhood pulmonary tuberculosis
Vitamin A status and therapy in childhood pulmonary tuberculosis
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DOI：
10.1016/s0022-3476(97)70046-5
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发表时间：
1997-12-01
影响因子：
5.1
通讯作者：
Hussey, GD
中科院分区：
文献类型：
--
作者：
Hanekom, WA;Potgieter, S;Hussey, GD
南非肺结核儿童的血浆维生素A水平较低（平均为18.1 ± 10.3 μ g/dl，低于正常值62%）。更广泛或更严重的疾病（例如，额外的肺外结核）和低水平的视黄醇结合蛋白、前白蛋白和白蛋白与低维生素A水平相关。高剂量维生素A治疗对疾病结局无影响。
Low plasma vitamin A levels (mean, 18.1 +/- 10.3 mu g/dl, 62% below normal) were demonstrated in South African children with pulmonary tuberculosis. More extensive or severe disease (e.g., additional extrapulmonary tuberculosis) and low levels of retinol binding protein, prealbumin, and albumin were associated with low vitamin A levels. High-dose vitamin A therapy had no effect on disease outcome.