CARDIOMYOPATHY AND MULTICORE MYOPATHY WITH ACCUMULATION OF INTERMEDIATE FILAMENTS
CARDIOMYOPATHY AND MULTICORE MYOPATHY WITH ACCUMULATION OF INTERMEDIATE FILAMENTS
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DOI：
10.1007/bf02072073
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发表时间：
1990-09-01
影响因子：
3.6
通讯作者：
BALLERINI, L
中科院分区：
文献类型：
--
作者：
BERTINI, E;BOSMAN, C;BALLERINI, L
一个女孩受限制性心肌病与神经肌肉参与描述。形态学检查显示多核肌病的模式，并与电子显微镜下的电子致密颗粒和丝状物质的肌浆积累被证明在骨骼肌和心脏。这种特殊的电子致密物质对应于肌肉和心脏纤维中结蛋白的增加，并在化学上得到证实。
A girl affected by a restrictive cardiomyopathy with neuromuscular involvement is described. Morphological examination showed a pattern of multicore myopathy and with electron microscopy a sarcoplasmic accumulation of electron dense granular and filamentous material was demonstrated both in skeletal muscle and heart. This peculiar electron dense material corresponded to increased desmin in muscle and cardiac fibres and was demonstrated immunohistochemically.