Lipid screening in children and adolescents in community practice: 2007 to 2010.
Lipid screening in children and adolescents in community practice: 2007 to 2010.
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DOI：
10.1161/circoutcomes.114.000842
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发表时间：
2014-09
期刊：
影响因子：
--
通讯作者：
O'Connor PJ
中科院分区：
文献类型：
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作者：
Margolis KL;Greenspan LC;Trower NK;Daley MF;Daniels SR;Lo JC;Kharbanda EO;Sinaiko AR;Magid DJ;Parker ED;Chandra M;Tavel HM;O'Connor PJ
Integrated guidelines on cardiovascular health and risk reduction in children issued in 2011 newly recommended universal screening for dyslipidemia in children at 9-11 years and 17-21 years. We determined the frequency and results of lipid testing in 301,080 children and adolescents aged 3-19 enrolled in three large U.S. health systems in 2007-2010 before the 2011 guidelines were issued. Overall, 9.8% of the study population was tested for lipids. The proportion tested varied by BMI percentile (5.9% of normal weight, 10.8% of overweight and 26.9% of obese children) and age (8.9% of 9-11 year olds and 24.3% of 17-19 year olds). In normal weight individuals, 2.8% of 9-11 year olds and 22.0% of 17-19 year olds were tested. In multivariable models, age and BMI category remained strongly associated with lipid testing. Sex, race, ethnicity, and blood pressure were weakly associated with testing. Abnormal lipid levels were found in 8.6% for total cholesterol, 22.5% for HDL-C, 12.0% for non-HDL-C, 8.0% for LDL-C and 21% for triglycerides (age 10-19). There was a strong and graded association of abnormal lipid levels with BMI, particularly for HDL-C and triglycerides (2- to 6-fold higher odds ratio in obese compared with normal weight children). Lipid screening was uncommon in 9-11 year olds and was performed in a minority of 17-19 year olds during 2007-2010. These data serve as a benchmark for assessing change in practice patterns after the new recommendations for pediatric lipid screening and management.
