Predicting emotional responses to potentially traumatic events from pre-exposure waking cortisol levels: a longitudinal study of police and firefighters.
Predicting emotional responses to potentially traumatic events from pre-exposure waking cortisol levels: a longitudinal study of police and firefighters.
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根据暴露前清醒皮质醇水平预测对潜在创伤事件的情绪反应：对警察和消防员的纵向研究。
DOI：
10.1080/10615806.2012.672976
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Orr,ScottP
中科院分区：
文献类型：
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作者：
Pineles,SuzanneL;Rasmusson,AnnM;Yehuda,Rachel;Lasko,NatashaB;Macklin,MichaelL;Pitman,RogerK;Orr,ScottP
有大量文献表明，经历过创伤性事件的个体在下丘脑-垂体-肾上腺（HPA）轴上有改变。然而，现有的文献并没有说明这些改变在多大程度上代表了暴露于重大压力源时发展为精神病理的预先存在的风险因素。在当前的研究中，我们检测了60名消防员和警察受训人员在训练期间和暴露于高压力潜在创伤事件（PTE）后的清醒唾液皮质醇水平与生理、人格和心理测量之间的关系。在训练期间评估时，清醒时的皮质醇与神经质呈负相关，但与对大声音调和恐惧条件反射的生理反应呈正相关。纵向上，PTE前醒来皮质醇与PTE后负性情绪和焦虑症状呈显著负相关，但PTE前醒来皮质醇与PTE后回忆PTE时的生理反应性呈正相关（趋势），因此，醒来皮质醇水平可用于预测PTE后不同类型的情绪后遗症。
There is a large literature demonstrating that individuals who have experienced traumatic events have alterations in the hypothalamic-pituitary-adrenal (HPA) axis. However, the existing literature does not address the extent to which these alterations represent pre-existing risk factors for developing psychopathology upon exposure to a significant stressor. In the current study, we examined the relationship between waking salivary cortisol level and physiological, personality, and psychological measures in 60 firefighters and police trainees during training, and then again after exposure to a highly stressful, potentially traumatic event (PTE). Waking cortisol was negatively associated with neuroticism, but positively associated with physiological reactivity to loud tones and fear conditioning when assessed during training. Longitudinally, there were significant negative correlations between pre-PTE waking cortisol and post-PTE negative mood and anxiety symptoms, but a positive correlation (trend) between pre-PTE waking cortisol and post-PTE physiological reactivity during recollection of the PTE. Thus, waking cortisol level may serve to predict divergent types of emotional sequelae following PTEs.