Characterizing amnesic patients for neurobehavioral study.
Characterizing amnesic patients for neurobehavioral study.
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表征健忘症患者的神经行为研究。
DOI：
10.1037//0735-7044.100.6.866
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发表时间：
1986
影响因子：
1.9
通讯作者：
Shimamura,AP
中科院分区：
文献类型：
--
作者：
Squire,LR;Shimamura,AP
在过去的100年里，对失忆症患者的神经心理学测试为了解正常记忆的结构和组织提供了一种有价值的方法。这项工作的一个复杂特征是，健忘症患者的损伤模式不同，除了导致健忘症的损伤之外，还存在什么损害。因此，随着对失忆症患者提出的问题变得越来越复杂，在每一组研究患者中，获取有关记忆损伤的严重程度和选择性的信息变得越来越重要。本文考虑了几种记忆测试和其他认知测试的适用性，目的是表征失忆症患者。这些测试的数据来自10名失忆症患者（6名患有Korsakoff综合征，3名因缺氧或缺血而失忆症，病例NA），这些患者构成了我们的研究患者群体，以及两个对照组。大多数测试的数据也适用于双侧电休克治疗后出现健忘症的患者。如果一个实验室发表的研究结果要为其他实验室对不同患者的研究提供基础，那么出现在实验文章“主题”部分的患者神经心理学描述需要扩展和标准化。
During the past 100 years, neuropsychological testing of amnesic patients has provided a valuable method for learning about the structure and organization of normal memory. One complicating feature of this work is the fact that amnesic patients differ in terms of the pattern of their lesions and in terms of what damage is present in addition to the lesions that cause amnesia. Accordingly, as the questions asked of amnesic patients have become more sophisticated, it has become increasingly important in every group of study patients to obtain information about both the severity and the selectiveness of memory impairment. The present article considers the suitability of several memory tests and other cognitive tests for the purpose of characterizing amnesic patients. Data from these tests are presented for 10 amnesic patients (6 with Korsakoff’s syndrome, 3 with amnesia owing to anoxia or ischemia, and case NA), who constitute our standing population of study patients, and for two control groups. Data from most of the tests are also presented for patients who were amnesic following bilateral electroconvulsive therapy. Neuropsychological descriptions of patients, which appear in the Subjects section of experimental articles, need to be expanded and standardized if published findings from one laboratory are to provide a foundation for work in other laboratories with different study patients.