Body flexibility and incident hypertension: The Niigata wellness study
Body flexibility and incident hypertension: The Niigata wellness study
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DOI：
10.1111/sms.13867
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发表时间：
2020-11-18
影响因子：
4.1
通讯作者：
Sone, Hirohito
中科院分区：
文献类型：
--
作者：
Gando, Yuko;Sawada, Susumu S.;Sone, Hirohito
高水平的身体素质，尤其是心肺健康，与较低的高血压发病率相关。然而，作为身体素质组成部分的灵活性与高血压发病率之间的关系尚不清楚。本研究的目的是通过队列研究探讨灵活性与高血压发病率之间的关系。本研究共纳入 22,972 名血压正常的参与者（14,805 名男性和 8167 名女性；中位年龄 49 岁）。 2001年4月至2002年3月期间，使用站立躯干屈曲计测量灵活性（站立前屈）。参与者按性别和年龄组分为灵活性四分位数。高血压的定义为收缩压≥140mmHg，舒张压≥90mmHg，或在2002年4月至2008年3月期间健康检查时自我报告既往诊断出高血压病史或当前正在服用高血压药物。在调整年龄、性别、体重指数、运动后，使用Cox比例风险模型估计高血压发病率的风险比和95%置信区间(95%CI)习惯、吸烟状况和饮酒状况。在 102,948 人年的随访期间（中位时间 5.6 年），4235 名参与者出现高血压。与最低灵活性（四分位数 1）相比，第二四分位数的风险比和 95% CI 分别为 0.96（0.88 - 1.04）、第三四分位数为 0.94（0.86 - 1.03）、第四四分位数为 0.83（0.76 - 0.91）。高水平的灵活性与较低的高血压发病率相关，与其他混杂因素无关。
A high level of physical fitness, especially cardiorespiratory fitness, is associated with lower incidence of hypertension. However, the relationship between flexibility, which is a component of physical fitness, and the incidence of hypertension is unknown. The purpose of this study was to investigate the relationship between flexibility and the incidence of hypertension in a cohort study. A total of 22,972 (14,805 men and 8167 women; median age 49 years) normotensive participants were included in this study. Between April 2001 and March 2002, flexibility (standing forward bending) was measured using a standing trunk flexion meter. The participants were divided into quartiles of flexibility by sex and age group. Hypertension was defined as systolic blood pressure >= 140 mm Hg, diastolic blood pressure >= 90 mm Hg, or a self-reported history of previously diagnosed hypertension or current medication for hypertension at a health examination between April 2002 and March 2008. Hazard ratios and 95% confidence intervals (95% CI) for the incidence of hypertension were estimated using Cox proportional hazards models after adjusting for age, sex, body mass index, exercise habits, smoking status, and drinking status. During 102,948 person years of follow-up (median 5.6 years), 4235 participants developed hypertension. Compared with the lowest flexibility (quartile 1), hazard ratios and 95% CI were 0.96 (0.88 - 1.04) for quartile 2, 0.94 (0.86 - 1.03) for quartile 3, and 0.83 (0.76 - 0.91) for quartile 4. A high level of flexibility was associated with lower incidence of hypertension, independent of other confounding factors.