Reporting and Replicating Trials of Exercise-Based Cardiac Rehabilitation Do We Know What the Researchers Actually Did?
Reporting and Replicating Trials of Exercise-Based Cardiac Rehabilitation Do We Know What the Researchers Actually Did?
复制标题
DOI：
10.1161/circoutcomes.114.001381
复制
发表时间：
2015-03-01
影响因子：
6.9
通讯作者：
Hoffmann, Tammy
中科院分区：
文献类型：
--
作者：
Abell, Bridget;Glasziou, Paul;Hoffmann, Tammy
背景-完整报告复杂干预措施的所有组成部分对于将研究证据转化为临床实践至关重要。以前的工作已经强调了非药物干预的报告的不足之处，但是，报告质量的运动为基础的干预冠心病还没有被examined.Methods和Results-A系统的搜索策略，以确定随机对照试验的运动为基础的心脏康复发表，直到2013年12月。纳入了57项试验，报告了74项干预措施。使用干预描述和复制检查表模板评估干预描述完整性。然后从其他已发表的材料中寻找缺失的干预措施详细信息，并通过电子邮件发送给相应的作者。只有6项干预措施（8%）充分描述了主要出版物中的所有要求项目;在检索其他已发表材料后增加到11项（15%），在联系试验作者后增加到32项（43%）。尽管在出版物中一直很好地报告了位置/设置和持续时间，但超过一半的干预措施（分别为42%和36%的干预措施）缺少运动时间表的完整描述以及有关其定制和进展的详细信息。虽然一些作者（25/61）能够提供缺失的干预细节时，联系，其他人无法找到（20）或没有回应（16）。结论心脏康复干预措施的报告不足是一个重大问题，基本信息经常丢失，几乎一半的干预措施，出版后无法获得。认真努力解决这个问题，可以促进心脏康复在临床实践中提供的质量的提高。
Background-Complete reporting of all components of complex interventions is essential for translation of research evidence into clinical practice. Previous work has highlighted deficiencies in the reporting of nonpharmacological interventions; however, the reporting quality of exercise-based interventions for coronary heart disease has not been examined.Methods and Results-A systematic search strategy was used to identify randomized controlled trials of exercise-based cardiac rehabilitation published until December 2013. Fifty-seven trials were included, reporting on 74 interventions. Intervention description completeness was assessed using the Template for Intervention Description and Replication checklist. Missing intervention details were then sought from additional published material and also by emailing corresponding authors. Only 6 interventions (8%) sufficiently described all required items within the main publication; this increased to 11 (15%) after searching for additional published material and 32 (43%) after contacting trial authors. Although location/setting and duration were consistently well reported in publications, complete descriptions of the exercise schedule, as well as details about its tailoring and progression, were missing for over half of interventions (complete for 42% and 36% of interventions, respectively). Although some authors (25/61) were able to provide missing intervention details when contacted, others could not be located (20) or did not respond (16).Conclusions-Inadequate reporting of cardiac rehabilitation interventions is a substantial problem, with essential information frequently missing, and for almost half of all interventions, unobtainable after publication. A conscientious effort to address this problem could facilitate an improvement in the quality of cardiac rehabilitation delivered in clinical practice.