The emphysematous and bronchial types of chronic airways obstruction. A clinicopathological study of patients in London and Chicago.
The emphysematous and bronchial types of chronic airways obstruction. A clinicopathological study of patients in London and Chicago.
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慢性气道阻塞的肺气肿型和支气管型。
DOI：
10.1016/s0140-6736(66)90181-4
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发表时间：
1966
期刊：
影响因子：
168.9
通讯作者：
J. S. Wootliff
中科院分区：
文献类型：
--
作者：
B. Burrows;C. Fletcher;B. Heard;N. Jones;J. S. Wootliff
描述了一项试验，比较了晚期乳腺癌患者立即接受垂体切除术或肾上腺切除术治疗，并且没有以前的激素治疗（“手术”）与那些在手术前接受激素治疗（“保守”）的患者。191例患者被纳入试验，治疗选择由随机抽样决定。两组的生存率和缓解率非常相似，预期寿命仅相差0-1个月。在复发的第一个迹象和以前没有激素治疗的情况下进行肾上腺切除术或垂体切除术对病人没有好处。这些数字并不表明对激素治疗的反应可以指导随后的肾上腺切除术或垂体切除术的反应。
A trial is described comparing patients with advanced breast cancer treated immediately by hypophysectomy or adrenalectomy and without previous hormone therapy (" operation") with those who were treated by hormones before operation (" conservative"). 191 patients were included in the trial and the choice of therapy was made by random sample. The survival and remission rates between the two groups were very similar and the expectation of life differed only by 0-1 month. There was no advantage to the patient in carrying out adrenal-ectomy or hypophysectomy at the first sign of recurrence and without previous hormone therapy. The figures do not indicate that the response to hormone therapy gives a guide to the response to subsequent adrenalectomy or hypophysectomy.