SBOLDesigner 2: An Intuitive Tool for Structural Genetic Design
SBOLDesigner 2: An Intuitive Tool for Structural Genetic Design
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DOI：
10.1021/acssynbio.6b00275
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发表时间：
2017-07-01
影响因子：
4.7
通讯作者：
Myers, Chris J.
中科院分区：
文献类型：
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作者：
Zhang, Michael;McLaughlin, James Alastair;Myers, Chris J.
随着合成生物学开放语言 (SBOL) 数据和可视化标准以详细且可重复的方式描述基因设计而获得认可，越来越需要生物学家可以使用支持这些标准的直观序列编辑器工具。本文介绍了 SBOLDesigner 2，它是一种基因设计自动化 (GDA) 工具，本身支持 SBOL 数据模型（版本 2）和 SBOL Visual（版本 1）。该软件能够从 SBOL 存储库（例如 SynBioHub）获取和存储零件和设计。它还可以以 FASTA、GenBank 和 SBOL 1 数据格式导入和导出有关零件和设计的数据。最后，它拥有简单直观的用户界面。本文描述了使用 SBOLDesigner 2 的设计过程，重点介绍了较早期原型版本的新功能。 SBOLDesigner 2 在 Apache 2.0 许可证下免费发布并开源。
As the Synthetic Biology Open Language (SBOL) data and visual standards gain acceptance for describing genetic designs in a detailed and reproducible way, there is an increasing need for an intuitive sequence editor tool that biologists can use that supports these standards. This paper describes SBOLDesigner 2, a genetic design automation (GDA) tool that natively supports both the SBOL data model (Version 2) and SBOL Visual (Version 1). This software is enabled to fetch and store parts and designs from SBOL repositories, such as SynBioHub. It can also import and export data about parts and designs in FASTA, GenBank, and SBOL 1 data format. Finally, it possesses a simple and intuitive user interface. This paper describes the design process using SBOLDesigner 2, highlighting new features over the earlier prototype versions. SBOLDesigner 2 is released freely and open source under the Apache 2.0 license.