Intracranial saccular aneurysm enlargement determined using serial magnetic resonance angiography
Intracranial saccular aneurysm enlargement determined using serial magnetic resonance angiography
复制标题
DOI：
10.3171/jns.2002.97.5.1023
复制
发表时间：
2002-11-01
影响因子：
4.1
通讯作者：
Piepgras, DG
中科院分区：
文献类型：
--
作者：
Phan, TG;Huston, J;Piepgras, DG
对象。本研究的目的是通过连续磁共振血管造影来确定未破裂颅内动脉瘤扩大的频率，并探讨动脉瘤特征和人口统计学因素是否能预测动脉瘤大小的变化。回顾性回顾了57例62例未破裂、未经治疗的囊状动脉瘤的MR血管造影。57例患者中55例无蛛网膜下腔出血史。在MR源图像上对这些病变的最大直径进行三次测量的方法确定了动脉瘤的大小。中位随访期为47个月（平均50个月，范围17-90个月）。随访期间无动脉瘤破裂。4例（7%）患者的动脉瘤体积增大。直径小于9毫米的动脉瘤没有变大，而9个初始直径大于或等于9毫米的动脉瘤中有4个（44%）的尺寸增大。预测动脉瘤生长的因素包括病变的大小（p < 0.001）和多叶的存在（p = 0.021）。动脉瘤的位置并不能预测增大的风险。中型或大型动脉瘤患者以及多叶动脉瘤患者可能会增加动脉瘤生长的风险，如果动脉瘤未得到治疗，则应进行mri随访。
Object. The goal of this study was to determine the frequency of enlargement of unruptured intracranial aneurysms by using serial magnetic resonance (MR) angiography and to investigate whether aneurysm characteristics and demographic factors predict changes in aneurysm size.Methods. A retrospective review of MR angiograms obtained in 57 patients with 62 unruptured, untreated saccular aneurysms was performed. Fifty-five of the 57 patients had no history of subarachnoid hemorrhage. The means of three measurements of the maximum diameters of these lesions on MR source images defined the aneurysm size. The median follow-up period was 47 months (mean 50 months, range 17-90 months).No aneurysm ruptured during the follow-up period. Four patients (7%) harbored aneurysms that had increased in size. No aneurysms smaller than 9 mm. in diameter grew larger, whereas four (44%) of the nine aneurysms with initial diameters of 9 mm or larger increased in size. Factors that predicted aneurysm growth included the size of the lesion (p < 0.001) and the presence of multiple lobes (p = 0.021). The location of the aneurysm did not predict an increased risk of enlargement.Conclusions. Patients with medium-sized or large aneurysms and patients harboring aneurysms with multiple lobes may be at increased risk for aneurysm growth and should be followed up with MR imaging if the aneurysm is left untreated.