Poor prognostic impact of delirium: especially on mortality and institutionalisation.
Poor prognostic impact of delirium: especially on mortality and institutionalisation.
复制标题
谵妄的不良预后影响：尤其是对死亡率和住院治疗。
DOI：
10.1111/psyg.12914
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发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Inada T.
中科院分区：
文献类型：
--
作者：
Tachibana M;Inada T.
精神错乱的病程与医院费用增加、医疗保健并发症、死亡率增加和长期不良结果有关。尽管精神错乱一直被认为是疾病患者最重要的预后因素之一，但人们对精神错乱的了解仍然很少，有效的治疗选择有限，而且还没有建立有效的治疗方法。本综述评估了精神错乱在不同情况下对死亡率、制度化和痴呆症的影响，以阐明其预后的严重性，阐明临床实践和未来研究的重要领域。妄想对新冠肺炎患者死亡率的影响与其他疾病相似。在18岁至65岁的精神错乱患者中，精神错乱对死亡率的影响可能高于65岁以上的精神错乱患者，但研究很少。需要促进所有年龄段的人对精神错乱的认识。如果仔细注意年轻患者中导致精神错乱的特定因素，医疗保健提供者可能能够减少精神错乱对临床结果的不良影响。目前临床实践中对精神错乱的干预措施(如镇静)与预后之间的相关性缺乏评估，进一步的临床研究是必要的。
The course of delirium is associated with increased hospital costs, healthcare complications, increased mortality, and long‐term poor outcomes. Despite delirium being long recognised as one of the most important prognostic components of patients with illnesses, delirium remains poorly understood, effective management options are limited, and no effective treatment has yet been established. This review evaluated the effects of delirium on mortality, institutionalisation, and dementia in various situations to clarify its prognostic seriousness to elucidate important areas for clinical practice and future research. The effect of delirium on mortality in COVID‐19 patients was similar to that in other diseases. The effect of delirium on mortality in patients with delirium between the ages of 18 and 65 may be higher than in those with delirium aged over 65, but studies are scarce. Promoting recognition of delirium at all ages is needed. With careful attention to the specific factors in younger patients that contribute to delirium, healthcare providers may be able to decrease the poor impact of delirium on clinical outcomes. Evaluation of the association between interventions for delirium such as sedation in present clinical practice and the prognosis of delirium is lacking, and further clinical studies are essential.