Thiazolidine-2-carboxylate derivatives formed from glyoxylate and L-cysteine or L-cysteinylglycine as possible physiological substrates for D-aspartate oxidase.
Thiazolidine-2-carboxylate derivatives formed from glyoxylate and L-cysteine or L-cysteinylglycine as possible physiological substrates for D-aspartate oxidase.
复制标题
由乙醛酸和 L-半胱氨酸或 L-半胱氨酰甘氨酸形成的噻唑烷-2-羧酸酯衍生物作为 D-天冬氨酸氧化酶的可能生理底物。
DOI：
10.1016/0006-291x(84)91388-3
复制
发表时间：
1984
影响因子：
3.1
通讯作者：
Hamilton,GA
中科院分区：
文献类型：
--
作者：
Burns,CL;Main,DE;Buckthal,DJ;Hamilton,GA
Adducts of glyoxylate with L-cysteine or L-cysteinylglycine were found to be excellent substrates at low concentrations for beef kidney D-aspartate oxidase. Evidence is presented thatcis-thiazolidine-2,4-dicarboxylate and its glycine amide are the actual substrates, and that both are converted in the enzymic reaction to 4-substituted thiazoline-2-carboxylates. The results imply that these thiazolidine derivatives are the likely physiological reactants for mammalian D-aspartate oxidase.
