Demographic risk factors for severe and fatal vivax and falciparum malaria among hospital admissions in northeastern Indonesian Papua
Demographic risk factors for severe and fatal vivax and falciparum malaria among hospital admissions in northeastern Indonesian Papua
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DOI：
10.4269/ajtmh.2007.77.984
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发表时间：
2007-11-01
影响因子：
3.3
通讯作者：
Baird, J. Kevin
中科院分区：
文献类型：
--
作者：
Barcus, Mazie J.;Basri, Hasan;Baird, J. Kevin
1998年1月至2000年12月，印度尼西亚新几内亚(巴布亚)东北部的查亚普拉省公立医院收治了5936名确诊为疟疾的患者。入院时镜检诊断恶性疟3,976例(67%)，间日疟1,135例(19%)，疟疾8例(1%)，混合感染817例(14%)。约9%(367)的患者被归类为患有严重疟疾(277例恶性疟原虫、36例间日疟原虫、53例混合感染和1例间日疟原虫)，88例死亡(79例恶性疟/混合感染和9例间日疟)。恶性疟疾患者和间日疟患者的死亡风险无明显差别(OR=0.89；P=0.771)。与非妊娠妇女相比，妊娠妇女患重度疟疾(P=0.643)或死于重度疟疾(P=0.748)的风险不高。这项研究比较了每个人口的入院率(基于人口普查数据)、儿童与成人、孕妇与非孕妇以及城市/郊区居民与农村居民之间的寄生虫血症、发病率和死亡率。
Between January 1998 and December 2000, the Jayapura Provincial Public Hospital in northeastern Indonesian New Guinea (Papua) admitted 5,936 patients with a diagnosis of malaria. The microscopic diagnosis at admission was Plasmodium falciparum (3,976, 67 %), Plasmodium vivax (1,135, 19%), Plasmodium malariae (8, < 1%), and mixed species infections (817, 14%). Approximately 9% (367) of patients were classified as having severe malaria (277 P. falciparum, 36 P. vivax, 53 mixed infections, and 1 P. malariae) and 88 died (79 P. falciparum/mixed infections and 9 P. vivax). Risk of fatal outcomes among severe malaria patients was indistinguishable between those with falciparum versus vivax malaria (OR = 0.89; P = 0.771). Compared with non-pregnant women, pregnant women showed no higher risk of severe malaria (P = 0.643) or death caused by severe malaria (P = 0.748). This study compares admissions per population (based on census data), parasitemia, morbidity, and mortality among children versus adults, pregnant versus non-Pregnant women, and urban/suburban versus rural residents.