Lessons to be learned from 25 years of research investigating psychosocial interventions for cancer patients.
Lessons to be learned from 25 years of research investigating psychosocial interventions for cancer patients.
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DOI：
10.1097/ppo.0b013e3181bf51fb
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发表时间：
2009-09
期刊：
影响因子：
--
通讯作者：
Floyd AH
中科院分区：
文献类型：
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作者：
Moyer A;Knapp-Oliver SK;Sohl SJ;Schnieder S;Floyd AH
对癌症患者进行严格的心理社会干预研究面临许多挑战，包括鼓励他们加入研究，要求他们参与干预或成为控制条件的一部分，并为后续评估提供数据。在这里，我们强调了研究人员对癌症患者的社会心理干预提供的有关这些挑战的有价值的见解。巧妙地处理这些问题对于本研究的内部和外部有效性以及参与者的伦理待遇具有重要意义。对旨在提高癌症患者生活质量的调查干预措施的25年研究（包括488个独特项目）进行了系统回顾，其中包括研究报告中指出的挑战。其中提到的困难是，患者可能觉得不需要心理社会干预，因此可能对参加干预研究不感兴趣。那些确实觉得需要这种干预措施的患者可能会因为被随机分配到一个非首选组的前景而被阻止参加试验；如果他们参加了试验，如果他们被分配到对照组，他们可能会失望、退出或寻求额外的补偿性帮助。除了随机化，研究的其他方面可能会让参与者或潜在参与者感到不快，比如同意书的语言或被问到的问题的侵扰性。潜在的补救措施，例如研究意识干预、金钱激励、与癌症支持组织合作，以及使用考虑到优点考虑和进一步研究调查的偏好设计。
Conducting rigorous psychosocial intervention research with cancer patients has many challenges including encouraging them to join studies, asking them to engage in interventions or be part of control conditions, and to provide data over follow-up assessments. Here, we highlight valuable insights regarding such challenges provided by investigators studying psychosocial interventions for cancer patients. Handling these skillfully has important implications for the internal and external validity of this research and the ethical treatment of participants. Challenges noted in research reports included in a systematic review of 25 years of research (comprising 488 unique projects) investigating interventions designed to enhance cancer patients’ quality of life were compiled. Among the difficulties mentioned was the fact that patients may not feel the need for psychosocial interventions and thus may not be interested in joining an intervention study. Patients who do feel the need for such interventions may be deterred from joining trials by the prospect of being randomized to a non-preferred group; if they do join a trial, participants may be disappointed, drop out, or seek compensatory additional assistance if they are assigned to a control group. Apart from randomization, other aspects of research may be off-putting to participants or potential participants, such as the language of consent forms or the intrusiveness of questions being asked. Potential remedies, such as research awareness interventions, monetary incentives, partnering with cancer support organizations, and using designs that take preferences into account merit consideration and further research inquiry.