Bioactive properties of Sanguisorba minor L. cultivated in central Greece under different fertilization regimes
Bioactive properties of Sanguisorba minor L. cultivated in central Greece under different fertilization regimes
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DOI：
10.1016/j.foodchem.2020.127043
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发表时间：
2020-10-15
期刊：
影响因子：
8.8
通讯作者：
Ferreira, Isabel C. F. R.
中科院分区：
文献类型：
--
作者：
Finimundy, Tiane C.;Karkanis, Anestis;Ferreira, Isabel C. F. R.
本研究对不同施肥量（对照、半施和全施）下栽培的小葡萄的化学特性和生物活性进行了评价。共鉴定出22种酚类化合物，包括5种酚酸、7种黄酮类化合物和10种单宁类化合物。在未施肥（对照）的叶片中，水解单宁含量普遍存在，即血清素H-10。全速施肥（660 Kg/ha）的根中黄酮类化合物含量最高，主要是儿茶素及其异构体，而半速施肥（330 Kg/ha）的根中总酚类化合物含量最高，这是由于鞣花单宁含量较高（干浸出物含量为84 +/- 1 mg/g）。对鼠伤寒沙门菌（MBC = 0.44 mg/mL）的抑菌活性较好。此外，无论受精率如何，根样品对所有测试细胞系都有活性，而叶片样品仅对HeLa细胞系有效。综上所述，小葡萄可能是天然生物活性化合物的来源，而施肥可以增加酚类化合物的含量。
In this study, the chemical characterization and bioactive properties of S. minor cultivated under different fertilization rates (control, half rate and full rate) were evaluated. Twenty-two phenolic compounds were identified, including five phenolic acids, seven flavonoids and ten tannins. Hydrolysable tannins were prevalent, namely Sanguiin H-10, especially in leaves without fertilization (control). Roots of full-rate fertilizer (660 Kg/ha) presented the highest flavonoid content, mainly catechin and its isomers, whereas half-rate fertilizer (330 Kg/ha), presented the highest content of total phenolic compounds, due to the higher amount of ellagitannins (lambertianin C: 84 +/- 1 mg/g of dry extract). Antimicrobial activities were also promising, especially against Salmonella typhimurium (MBC = 0.44 mg/mL). Moreover, root samples revealed activity against all tested cell lines regardless of fertilization rate, whereas leaves were effective only against HeLa cell line. In conclusion, S. minor could be a source of natural bioactive compounds, while fertilization could increase phenolic compounds content.