Analysis of pressure-driven air bubble elimination in a microfluidic device
Analysis of pressure-driven air bubble elimination in a microfluidic device
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DOI：
10.1039/b712672g
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发表时间：
2008-01-01
期刊：
影响因子：
6.1
通讯作者：
Park, Je-Kyun
中科院分区：
文献类型：
--
作者：
Kang, Joo H.;Kim, Yu Chang;Park, Je-Kyun
我们报告了一种用于透气微流控装置的压力驱动气泡消除的分析。在这项研究中，我们用气体渗透模型描述了微流控装置中气泡的去除，并计算了气泡的去除效率。根据所施加的压力估算了简化模型的修正系数。基于所建立的模型，通过与实验结果的比较，表明将一定面积的滞留气泡排出所需的时间误差在11.58%以内。利用模型方程，我们能够完全消除在向微流控装置填充水溶液的过程中出现的气泡。
We report an analysis of pressure-driven bubble elimination for a gas-permeable microfluidic device. In this study, we described bubble elimination in a microfluidic device employing a gas permeation model and calculated the removal efficiency of bubbles. The correction factor for the simplified model was estimated with respect to the applied pressure. Based on the established model, the required time to remove a trapped bubble with a certain area was shown to be within an error of 11.58% by comparison with experimental results. Exploiting the model equation, we were able to completely remove the air bubbles appearing during the process of filling a microfluidic device with an aqueous solution.