The Reproductive Performance of the Laboratory Mouse
The Reproductive Performance of the Laboratory Mouse
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实验小鼠的生殖性能
DOI：
10.3181/00379727-126-32541
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发表时间：
1967
影响因子：
--
通讯作者：
M. Wohlfromm
中科院分区：
文献类型：
--
作者：
R. Rugh;M. Wohlfromm
当对一大群CF1雌性小鼠的生殖性能进行单独跟踪时，可以明显看出，第一胎是最小的，并且至少在第四胎时，体积逐渐变大。在13508只正常后代中，经过连续的交配程序，雄性占52.8%，雌性占47.2%。在未经处理的雌性CF1株中发现的异常小鼠数量并不高（2.29% ~ 3.26%），但从第1胎到第4胎逐次增加。在其他（“不正常”）小鼠中，有死亡和/或发育不良的胎儿，一些在出生时因不明原因被母亲吃掉，一些羊膜持续存在，还有一些异常，主要是中枢神经系统。首次怀孕的处女小鼠，无论是幼龄（3-5个月）还是大龄（7-9个月），其着床部位都不如7-9个月的多胎雌性小鼠多。多胎鼠的平均产仔数最大，比前繁殖鼠或任何年龄的处女的产仔数都要大。虽然在所有四种情况下，雄性的数量总是比雌性多，但由于某种原因，多胞胎的比例接近50/50。然而，必须指出的是，这些数据只涉及128窝，因此数据可能不像上面展示的那样可靠，因为这些数据来自一组大得多的老鼠。
Summary When a large group of CF1 female mice are followed individually for their reproductive performance, it becomes evident that the first litter size is the smallest and the size gets progressively larger at least to the 4th litter. Among the 13,508 normal offspring examined, following continuous mating procedures, 52.8% were males and 47.2% were females. The number of abnormal mice found in otherwise untreated females of the CF1 strain is never high (2.29% to 3.26%), but it does increase with successive litters from the 1st to the 4th. Among the other (“not normal”) mice there were dead and/or stunted fetuses, some were eaten at birth by the mother for reasons unknown, some had persistent amnions, and others had anomalies, primarily of the central nervous system. Virgin mice becoming pregnant for the 1st time, whether young (3-5) months or older (7-9 months) do not have as many implantation sites as do the multipara females of 7-9 months. The average litter size is greatest among the multipara mice, more so than among the ex-breeders or virgins of any age. While males are always produced in greater mimbers than females, in all 4 categories, for some reason the multiparas approach closest to a 50/50 ratio. It must be pointed out, however, that these data involve only 128 litters so that the data may not be as reliable as that presented above, from a vastly larger group of mice.