Environmental stress and blood glucose change in insulin-dependent diabetes mellitus.
Environmental stress and blood glucose change in insulin-dependent diabetes mellitus.
复制标题
环境压力和胰岛素依赖型糖尿病的血糖变化。
DOI：
10.1037//0278-6133.9.5.503
复制
发表时间：
1990
期刊：
影响因子：
--
通讯作者：
Clarke,WL
中科院分区：
文献类型：
--
作者：
Gonder-Frederick,LA;Carter,WR;Cox,DJ;Clarke,WL
胰岛素依赖型糖尿病（IDDM）患者的血糖（BG）对心理应激的反应尚未得到明确的证实。我们报告一项研究，旨在解决审查的差距和方法上的困难。受试者与胰岛素依赖型糖尿病暴露于两个会议（相隔12周）的两个20分钟的标准化的压力（主动和被动）和控制条件管理的平衡秩序。为了测量BG反应，将受试者连接到提供连续BG测量的葡萄糖/胰岛素输注系统。情绪检查表的措施，获得在前，后应激，和恢复期。在第一次测试期间，主动应激与BG反应的绝对变化显著大于被动应激。结果还表明，胰岛素依赖型糖尿病受试者的BG反应，这种积极的压力是特质，但随着时间的推移显着可靠。
Blood glucose (BG) response to psychological stress in insulin-dependent diabetes mellitus (IDDM) patients has not been firmly established. We report a study designed to address the gaps and methodological difficulties reviewed. Subjects with IDDM were exposed to two sessions (12 weeks apart) of two 20-min standardized stressors (active and passive) and a control condition administered in counterbalanced order. To measure BG response, subjects were connected to a glucose/insulin infusion system providing continuous BG measurement. Mood checklist measures were obtained at prestressor, poststressor, and recovery periods. During the first session of testing, the active stressor was associated with significantly more absolute change in BG response than the passive stressor. Results also indicate that IDDM subjects’ BG response to this active stressor was idiosyncratic but significantly reliable over time.