Lead, mercury, and cadmium in blood and their relation to diet among Swedish adults
Lead, mercury, and cadmium in blood and their relation to diet among Swedish adults
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DOI：
10.1016/j.fct.2013.03.024
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发表时间：
2013-07-01
影响因子：
4.3
通讯作者：
Darnerud, Per Ola
中科院分区：
文献类型：
--
作者：
Bjermo, Helena;Sand, Salomon;Darnerud, Per Ola
本研究的目的是检查铅（Pb），汞（Hg），镉（Cd）在瑞典成年人的血液中的身体负担和血液水平之间的关联，饮食和其他生活方式factors.The研究是基于一个亚组（n = 273）的全国调查Riksmaten 2010-2011（4天的食物记录和问卷）。用质谱或荧光光谱法测定全血中的铅、汞和镉，并测定尿中的镉，血中重金属的中位数（5- 95分位数）如下：铅：13.4（5.8-28.6）μ g/L，汞：1.13（0.31-3.45）μ g/L，镉：0.19（0.09-1.08）μ g/L。这三种金属都随着年龄的增长而增加。血液中的铅水平呈正相关的游戏和酒精的摄入量，汞与鱼类的摄入量，和血液镉相关的吸烟和低铁存储和低肉类intake.Body负担的研究金属一般低于健康为基础的参考值，但几个人的血液铅水平高于参考点可能的肾毒性和发育神经毒性的影响。由于不能排除对健康的影响，高铅暴露的个人应致力于减少其身体负担，包括食物和其他暴露途径。(c)2013爱思唯尔有限公司保留所有权利。
The aim of the present study was to examine the body burden of lead (Pb), mercury (Hg), and cadmium (Cd) in blood among Swedish adults and the association between blood levels, diet and other lifestyle factors.The study was based on a subgroup (n = 273) of the national survey Riksmaten 2010-2011 (4-day food records and questionnaire). Lead, Hg, and Cd were measured in whole blood, and Cd additionally in urine, by mass or fluorescence spectrometry methods.The median values (5-95th percentiles) of the metals in blood were as follows: Pb: 13.4 (5.8-28.6) mu g/L, Hg: 1.13 (0.31-3.45) mu g/L, and Cd: 0.19 (0.09-1.08) mu g/L. All three metals increased with increasing age. Lead levels in blood were positively associated with intakes of game and alcohol, Hg was related to fish intake, and blood Cd related to smoking and low iron stores and to a low meat intake.Body burdens of the studied metals were generally below health based reference values, but several individuals had blood Pb levels above the reference point for possible nephrotoxic and developmental neurotoxic effects. As health effects cannot be excluded, individuals with high Pb exposure should aim at decreasing their body burden, both from food and from other exposure routes. (c) 2013 Elsevier Ltd. All rights reserved.