Home-based Aerobic Exercise and Resistance Training in Peritoneal Dialysis Patients: A Randomized Controlled Trial
Home-based Aerobic Exercise and Resistance Training in Peritoneal Dialysis Patients: A Randomized Controlled Trial
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DOI：
10.1038/s41598-019-39074-9
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发表时间：
2019-02-22
影响因子：
4.6
通讯作者：
Itoh, Hiroshi
中科院分区：
文献类型：
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作者：
Uchiyama, Kiyotaka;Washida, Naoki;Itoh, Hiroshi
有氧和阻力训练对腹膜透析（PD）患者的潜在影响已经部分阐明。我们调查了家庭运动计划对PD患者身体功能和健康相关生活质量（HRQOL）的影响。患者被随机分为运动组（n = 24）和常规护理组（n = 23）。运动患者每周在家进行3次有氧运动和2次阻力训练，为期12周。常规护理患者未接受特殊干预。与常规护理组相比，运动组的增量穿梭行走测试距离显著提高（P = 0.02）。在使用肾脏疾病短生命质量问卷评估的HRQOL亚量表中，运动组的肾脏疾病成分总结（P = 0.03）、身体角色功能（P = 0.01）、情感角色功能（P < 0.01）和角色/社会成分总结（P < 0.01）显著改善。此外，运动组血清白蛋白明显维持（P = 0.03）。没有与干预相关的不良事件报告。据我们所知，这是第一个随机对照试验，表明12周的家庭锻炼计划对PD患者有益。
Potential effects of aerobic and resistance training in peritoneal dialysis (PD) patients have been partially elucidated. We investigated effects of a home-based exercise program on physical functioning and health-related quality of life (HRQOL) in PD patients. Patients were randomly assigned to exercise (n = 24) and usual care (n = 23) groups. The exercise patients performed aerobic exercise thrice weekly and resistance training twice weekly at home for 12 weeks. The usual care patients received no specific intervention. The distance in incremental shuttle walking test significantly improved in the exercise group compared with the usual care group (P = 0.02). Among the HRQOL subscales assessed using the Kidney Disease Quality of Life-Short Form questionnaire, kidney disease component summary (P = 0.03), physical role functioning (P = 0.01), emotional role functioning (P < 0.01), and role/social component summary (P < 0.01) significantly improved in the exercise group. Moreover, serum albumin was significantly maintained in the exercise group (P = 0.03). There were no reported adverse events associated with the intervention. To our knowledge, this is the first randomized controlled trial to indicate the beneficial effects of a 12-week home-based exercise program exclusively in PD patients.