Interpretation of nevirapine concentration from immunochromatographic strip test using support vector regression
Interpretation of nevirapine concentration from immunochromatographic strip test using support vector regression
复制标题
DOI：
10.1109/icma.2008.4798830
复制
发表时间：
2008-08
期刊：
影响因子：
--
通讯作者：
Ekkalak Sumonphan;S. Auephanwiriyakul;N. Theera-Umpon
中科院分区：
文献类型：
--
作者：
Ekkalak Sumonphan;S. Auephanwiriyakul;N. Theera-Umpon
对接受奈韦拉平（NVP）治疗的人类免疫缺陷病毒（HIV）患者进行随访是评估耐药性和HIV突变的必要过程。通常也通过免疫层析（IC）试纸条测试进行测试。然而，通过目视颜色很难估计患者获得的药物量。本研究提出了使用支持向量回归（SVR）评估 IC 试纸条测试中药物浓度的方法。将所提出方法的结果与多层感知器（MLP）获得的结果进行比较。结果发现，SVR 比 MLP 产生更高的精度。
Follow-up of human immunodeficiency virus (HIV) patients treated with nevirapine (NVP) is a necessary process to evaluate the drug resistance and the HIV mutation. It is also usually tested by immunochromatographic (IC) strip test. However, it is difficult to estimate the amount of drug the patient gets by visually inspection of color. This study proposes the method of evaluating the drug concentration from IC strip test using support vector regression (SVR). The results from the proposed method are compared with the result obtained from multilayer perceptrons (MLP). It is found that SVR produce higher accuracy than MLP.