Screening of novel microbial enzymes for the production of biologically and chemically useful compounds.
Screening of novel microbial enzymes for the production of biologically and chemically useful compounds.
复制标题
筛选用于生产生物和化学有用化合物的新型微生物酶。
DOI：
--
复制
发表时间：
1997
期刊：
影响因子：
--
通讯作者：
Michihiko Kobayashi
中科院分区：
文献类型：
--
作者：
Sakayu Shimizu;J. Ogawa;M. Kataoka;Michihiko Kobayashi
酶在有机合成中被公认为是上级催化剂。特别是微生物被认为是有用酶的宝贵来源。利用微生物酶或微生物本身的合成技术称为微生物转化。在设计微生物转化过程中，最重要的一点是为感兴趣的反应找到合适的酶。在微生物中发现了各种新的特异性转化酶，并揭示了它们的潜在特性。本文回顾了我们目前的结果，发现新的酶的生物和化学有用的化合物的生产，并强调了在不同的微生物世界中筛选酶的重要性。
Enzymes have been generally accepted as superior catalysts in organic synthesis. Micro-organisms in particular have been regarded as treasure sources of useful enzymes. The synthetic technology using microbial enzymes or micro-organisms themselves is called microbial transformation. In designing a microbial transformation process, one of the most important points is to find a suitable enzyme for the reaction of interest. Various kinds of novel enzymes for specific transformations have been discovered in micro-organisms and their potential characteristics revealed. This article reviews our current results on the discovery of novel enzymes for the production of biologically and chemically useful compounds, and emphasizes the importance of screening enzymes in a diverse microbial world.
白三烯生物合成的脂肪酸结构要求。
DOI：
10.1016/s0090-6980(80)80057-8
发表时间：
1980
期刊：
Prostaglandins
影响因子：
--
作者：
Jakschik,BA;Sams,AR;Sprecher,H;Needleman,P
通讯作者：
Needleman,P