Morphological variation of a lipid vesicle confined in a spherical vesicle
Morphological variation of a lipid vesicle confined in a spherical vesicle
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限制在球形囊泡中的脂质囊泡的形态变化
DOI：
10.1103/physreve.89.040701
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发表时间：
2014
影响因子：
2.4
通讯作者：
and Hiroshi Noguchi
中科院分区：
文献类型：
--
作者：
Ai Sakashita;Masayuki Imai;and Hiroshi Noguchi
用快速激光共聚焦显微镜对双层囊泡的形态进行了实验研究，并用面积差弹性的动态三角膜层模型进行了数值模拟。在单层囊泡中观察不到的内囊泡形态：双孔和四孔小泡、裂隙小泡，以及形状各异的两室或三室小泡。模拟结果很好地再现了实验结果，一些形状转变可以用一个简单的轴对称形状的理论模型来解释。
Morphologies of a double-bilayer vesicle were explored experimentally by fast confocal laser microscopy and numerically by a dynamically triangulated membrane model with area-difference elasticity. The confinement was found to induce several shapes of the inner vesicles that had not been observed in unilamellar vesicles: double and quadruple stomatocytes, slit vesicle, and vesicles of two or three compartments with various shapes. The simulations reproduced the experimental results very well and some of the shape transitions can be understood by a simple theoretical model for axisymmetric shapes.