A tutorial in estimating the prevalence of disease in humans and animals in the absence of a gold standard diagnostic

A tutorial in estimating the prevalence of disease in humans and animals in the absence of a gold standard diagnostic
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DOI:
10.1186/1742-7622-9-9
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发表时间:
2012-12-28
影响因子:
2.3
通讯作者:
Torgerson, Paul R.
Torgerson, Paul R.
中科院分区:
其他
文献类型:
--
作者:
Lewis, Fraser I.;Torgerson, Paul R.

文献摘要

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在没有金标准诊断试验的情况下,估计人类和其他动物的疾病流行率的流行病学方法已经确立。尽管如此,报告表观流行率仍然是公共卫生研究和疾病控制方案中的标准做法,尽管表观流行率可能与疾病的真实流行率有很大不同。总结和回顾了估计真实患病率的方法。还提供了计算附录,其中包含如何使用免费软件轻松实现某些方法的简要指南。
Epidemiological methods for estimating disease prevalence in humans and other animals in the absence of a gold standard diagnostic test are well established. Despite this, reporting apparent prevalence is still standard practice in public health studies and disease control programmes, even though apparent prevalence may differ greatly from the true prevalence of disease. Methods for estimating true prevalence are summarized and reviewed. A computing appendix is also provided which contains a brief guide in how to easily implement some of the methods presented using freely available software.