Narrow band imaging in the diagnosis of intra-epithelial and invasive laryngeal squamous cell carcinoma: A preliminary report of two cases
Narrow band imaging in the diagnosis of intra-epithelial and invasive laryngeal squamous cell carcinoma: A preliminary report of two cases
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DOI：
10.1016/j.anl.2009.01.008
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发表时间：
2009-12-01
影响因子：
1.7
通讯作者：
Okamoto, Makito
中科院分区：
文献类型：
--
作者：
Masaki, Takashi;Katada, Chikatoshi;Okamoto, Makito
窄带成像（NBI）是一种新型光学技术，通过在红-绿-蓝顺序照明系统（CV-260 SL处理器和CLV-260 SL光源，Olympus Optical Co. Ltd，Tokyo，Japan）中使用窄带滤光片照明上皮内乳头状毛细血管环（IPCL），增强胃肠内窥镜（GIE）的诊断能力。选择NBI滤波器组（415 nm和540 nm）以获得微血管结构的精细图像。由于415 nm是血红蛋白的吸收带，因此在该波长下可以最清楚地看到粘膜表面的毛细血管。NBI能够更清楚地表示毛细血管模式和不同类型的组织之间的边界，这对于诊断处于早期阶段的肿瘤是必要的（Gono K，Yamazaki K，Doguchi N，Nonami T，Obi T Yamaguchi M等人，Endoscopic observation of tissue by narrow band illumination. Opt Rev 2003; 10：211-215，Gono K，Obi T，Yamaguchi M，Ohyama N，町田H，佐野Y等。窄带内窥镜成像中增强组织特征的外观。J Biomed Opt 2004;9：568-577）。我们报告了两例喉鳞状细胞癌患者，采用配备NBI的经鼻GIE评估其扩散和浸润深度。根据我们的研究结果，喉原位癌的血管肿瘤性改变可能与食管原位癌相似。(C)2009爱思唯尔爱尔兰有限公司保留所有权利。
Narrow band imaging (NBI) is a novel optical technique that enhances the diagnostic capability of the gastrointestinal endoscope (GIE) by illuminating the intraepithelial papillary capillary loop (IPCL) using narrow bandwidth filters in a red-green-blue sequential illumination system (CV-260SL processor and CLV-260SL light source, Olympus Optical Co. Ltd, Tokyo, Japan). The NBI filter sets (415 nm and 540 nm) are selected to obtain fine images of the microvascular structure. Because 415 nm is the hemoglobin absorption band, capillaries on the mucosal surface can be seen most clearly at this wavelength. NBI is able to represent more clearly both capillary patterns and the boundary between different types of tissue, which are necessary for diagnosing a tumor in its early stage (Gono K, Yamazaki K, Doguchi N, Nonami T, Obi T Yamaguchi M, et al. Endoscopic observation of tissue by narrow band illumination. Opt Rev 2003;10:211-215, Gono K, Obi T, Yamaguchi M, Ohyama N, Machida H, Sano Y, et al. Appearance of enhanced tissue feature in narrow-band endoscopic imaging. J Biomed Opt 2004;9:568-577).We present two patients with laryngeal squamous cell carcinoma in whom the spread and the depth of invasion was evaluated with transnasal GIE equipped with NBI. Based on our results, the vascular neoplastic changes of carcinoma in situ of the larynx could be similar to carcinoma in Situ of the esophagus. (C) 2009 Elsevier Ireland Ltd. All rights reserved.