Genetic Analysis of Blue Light-Induced Responses in Neurospora crassa
Genetic Analysis of Blue Light-Induced Responses in Neurospora crassa
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粗糙脉孢菌蓝光诱导反应的遗传分析
DOI：
10.1007/978-3-642-69767-8_24
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发表时间：
1984
期刊：
影响因子：
--
通讯作者：
V. Russo
中科院分区：
文献类型：
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作者：
F. Innocenti;V. Russo
到目前为止，蓝光感觉转导链的遗传分析基本上只在藻类真菌中完成。在这种生物中，人们发现两个基因，madA和madB，是五种不同效应的光诱导所必需的。这种多向性被认为是不同的光反应具有共同的早期步骤的迹象，包括光感受器[12，17，18]。藻霉的劣势在于它的遗传学以及它的生物化学还处于非常原始的阶段。相反，粗糙脉孢菌是研究最多的真核生物之一，从基因和生化角度都是众所周知的[15]。此外，还从光生物学的角度对其进行了研究(见下文)。整合来自遗传、生化和光生物学研究的信息的可能性使这种生物特别适合在分子水平上探讨光接收问题。
A genetic analysis of blue light sensory transduction chains has been done until now essentially only in Phycomyces. In this organism it was found that two genes, mad A and madB, are necessary for the photoinduction of five different effects. This pleiotropism has been considered an indication of the different photoresponses having their early steps in common, including the photoreceptor [12, 17, 18]. The disadvantage of Phycomyces lies in the fact that its genetics, as well as its biochemistry are still at a very primitive stage. On the contrary,Neurospora crassa, one of the most studied eukaryotic organisms, is well known from both a genetic [15] and from a biochemical point of view [6]. Furthermore, it has been studied also from a photobiological point of view (see below). The possibility of integrating information coming from genetic, biochemical, and photobiological studies makes this organism particularly suitable to approach the problem of photoreception at the molecular level.