Memory's echo: Vivid remembering reactivates sensory-specific cortex
Memory's echo: Vivid remembering reactivates sensory-specific cortex
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DOI：
10.1073/pnas.97.20.11125
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发表时间：
2000-09-26
影响因子：
11.1
通讯作者：
Buckner, RL
中科院分区：
文献类型：
--
作者：
Wheeler, ME;Petersen, SE;Buckner, RL
人类记忆中的一个基本问题是大脑在检索过程中如何表示特定于感官的信息。一种假设是，感觉皮层的区域在检索感觉特异性信息时被重新激活（1-3）。在这里，我们报告的结果，从一项研究中，受试者学习了一组图片和声音的项目，然后给予回忆测试，在此期间，他们生动地记住的项目，同时使用事件相关的功能磁共振成像成像，视觉和听觉皮层的区域被激活的差异，在检索的图片和声音，分别。此外，在回忆测试期间激活的区域包括在单独的感知任务期间激活的区域的子集，在该任务中，受试者实际上看到图片并听到声音。在回忆测试中被激活的区域被发现在后期比在早期的视觉和听觉皮层中更多。因此，结果表明，生动的视觉和听觉信息的检索可以与一些相同的感觉区域，在感知这些项目被激活的重新激活。
A fundamental question in human memory is how the brain represents sensory-specific information during the process of retrieval. One hypothesis is that regions of sensory cortex are reactivated during retrieval of sensory-specific information (1-3). Here we report findings from a study in which subjects learned a set of picture and sound items and were then given a recall test during which they vividly remembered the items while imaged by using event-related functional MRI, Regions of visual and auditory cortex were activated differentially during retrieval of pictures and sounds, respectively. Furthermore, the regions activated during the recall test comprised a subset of those activated during a separate perception task in which subjects actually viewed pictures and heard sounds. Regions activated during the recall test were found to be represented more in late than in early visual and auditory cortex. Therefore, results indicate that retrieval of vivid visual and auditory information can be associated with a reactivation of some of the same sensory regions that were activated during perception of those items.