The role of inflammation in age-related disease.
The role of inflammation in age-related disease.
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DOI：
10.18632/aging.100531
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发表时间：
2013-01
期刊：
影响因子：
--
通讯作者：
Sierra F
中科院分区：
文献类型：
--
作者：
Howcroft TK;Campisi J;Louis GB;Smith MT;Wise B;Wyss-Coray T;Augustine AD;McElhaney JE;Kohanski R;Sierra F
美国国立卫生研究院（NIH）老年科学兴趣小组（GSIG）主办的研讨会，炎症在糖尿病相关疾病中的作用，于2012年9月6日至7日在马里兰州贝塞斯达举行。现在认识到，轻度促炎状态与老年人的主要退行性疾病相关。研讨会的重点是更好地了解这种低水平慢性炎症的起源和后果，以便设计旨在改善健康状况的适当干预研究。四个会议探讨了内在的，环境暴露和免疫途径，通过这些途径，慢性炎症产生，持续，并导致年龄相关疾病。在研讨会结束时，确定了加快理解慢性病机制基础的建议。
The National Institutes of Health (NIH) Geroscience Interest Group (GSIG) sponsored workshop, The Role of Inflammation in Age-Related Disease, was held September 6th-7th, 2012 in Bethesda, MD. It is now recognized that a mild pro-inflammatory state is correlated with the major degenerative diseases of the elderly. The focus of the workshop was to better understand the origins and consequences of this low level chronic inflammation in order to design appropriate interventional studies aimed at improving healthspan. Four sessions explored the intrinsic, environmental exposures and immune pathways by which chronic inflammation are generated, sustained, and lead to age-associated diseases. At the conclusion of the workshop recommendations to accelerate progress toward understanding the mechanistic bases of chronic disease were identified.