An area specialized for spatial working memory in human frontal cortex
An area specialized for spatial working memory in human frontal cortex
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DOI：
10.1126/science.279.5355.1347
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发表时间：
1998-02-27
期刊：
影响因子：
56.9
通讯作者：
Haxby, JV
中科院分区：
文献类型：
--
作者：
Courtney, SM;Petit, L;Haxby, JV
工作记忆是保持信息的活跃表征以使其可供使用的过程。在猴子中，前额叶皮质区域对空间工作记忆很重要，位于主沟及其周围，但在人类中，空间工作记忆区域的位置甚至存在争议。通过在人类中使用功能磁共振成像，在额叶上沟中发现了一个专门用于空间工作记忆的区域。这一区域在人类大脑中的位置比在猴子大脑中的位置更靠前和更靠后，这可能解释了为什么以前没有识别出它。
Working memory is the proc!ss of maintaining an active representation of information so that it is available for use. In monkeys, a prefrontal cortical region important for spatial working memory lies in and around the principal sulcus, but in humans the location, and even the existence, of a region for spatial working memory is in dispute. By using functional magnetic resonance imaging in humans, an area in the superior frontal sulcus was identified that is specialized for spatial working memory. This area is located more superiorly and posteriorly in the human than in the monkey brain, which may explain why it was not recognized previously.