DIFFUSE BRAIN-SWELLING IN SEVERELY HEAD-INJURED CHILDREN - A REPORT FROM THE NIH TRAUMATIC COMA DATA-BANK
DIFFUSE BRAIN-SWELLING IN SEVERELY HEAD-INJURED CHILDREN - A REPORT FROM THE NIH TRAUMATIC COMA DATA-BANK
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DOI：
10.3171/jns.1992.76.3.0450
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发表时间：
1992-03-01
影响因子：
4.1
通讯作者：
YOUNG, HF
中科院分区：
文献类型：
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作者：
ALDRICH, EF;EISENBERG, HM;YOUNG, HF
在这项研究中，前瞻性地收集了753例重型颅脑损伤患者（111例儿童和642例成人）的数据，并检查弥漫性脑肿胀的证据及其与预后的关系。弥漫性脑肿胀在儿童（16岁及以下）中发生的频率大约是成人的两倍。在这些儿童中发现了较高的死亡率（53%），是无弥漫性脑肿胀儿童（16%）的三倍。患有弥漫性脑肿胀的成人死亡率（46%）与儿童相似，但仅略高于无弥漫性脑肿胀的成人（39%）。当弥漫性脑肿胀的诊断范围扩大到包括弥漫性脑肿胀合并小的脑实质出血（<15立方厘米）的患者时，这些死亡率几乎没有变化。
In this study, data were prospectively collected from 753 patients (111 children and 642 adults) with severe head injury and examined for evidence of diffuse brain swelling and its association with outcome. Diffuse brain swelling occurred approximately twice as often in children (aged 16 years or younger) as in adults. A high mortality rate (53%) was found in these children, which was three times that of the children without diffuse brain swelling (16%). Adults with diffuse brain swelling had a mortality rate (46%) similar to that of children, but only slightly higher than that for adults without diffuse brain swelling (39%). When the diagnosis of diffuse brain swelling was expanded to include patients with diffuse brain swelling plus small parenchymal hemorrhages (< 15 cu cm), these mortality rates were virtually unchanged.