HLA-DR-EXPRESSING LANGERHANS-LIKE CELLS IN VAGINAL AND CERVICAL EPITHELIUM

HLA-DR-EXPRESSING LANGERHANS-LIKE CELLS IN VAGINAL AND CERVICAL EPITHELIUM
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DOI:
10.3109/00016348309156253
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发表时间:
1983-01-01
影响因子:
4.3
通讯作者:
THORSBY, E
THORSBY, E
中科院分区:
医学2区
文献类型:
--
作者:
BJERCKE, S;SCOTT, H;THORSBY, E

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用兔抗HLA-DR抗原血清对乙醇固定、石蜡包埋的人阴道和外宫颈组织标本切片进行间接免疫荧光染色。观察到具有树突状外观的细胞的特异性染色。细胞随机分布,主要分布于复层鳞状上皮的副基底层细胞。树突状细胞的数量占宫颈上皮细胞总数的1-3%,占阴道上皮细胞总数的1-5%。这些细胞很可能是朗格汉斯细胞。
Sections of ethanol-fixed, paraffin-embedded tissue specimens from human vagina and exocervix were stained by an indirect immunofluorescence method with a rabbit antiserum to HLA-DR antigens. A specific staining of cells having a dendritic appearance was seen. The cells were randomly distributed, mainly in the parabasal cell layer of the stratified squamous epithelium. The number of dendritic cells was 1-3% of all cells in the cervical epithelium and 1-5% of the cells in the vaginal epithelium. Most probably these cells are Langerhans'' cells.